Evidence map›Paper›PMID 25229540›Full record

ArticlePloS one2014

Mechanical and in vitro biological performance of graphene nanoplatelets reinforced calcium silicate composite.

Mehdi Mehrali, Ehsan Moghaddam, Seyed Farid Seyed Shirazi, Saeid Baradaran, Mohammad Mehrali, Sara Tahan Latibari, Hendrik Simon Cornelis Metselaar, Nahrizul Adib Kadri, Keivan Zandi, Noor Azuan Abu Osman

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Role of TiScientific reports · 2024
    Article
  4. Article
  5. Ceramic Toughening Strategies for Biomedical Applications.Frontiers in bioengineering and biotechnology · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mehdi MehraliDepartment of Mechanical Engineering and Center of advanced Material, University of Malaya, Kuala Lumpur, Malaysia.
Ehsan MoghaddamTropical Infectious Diseases Research and Education Centre (TIDREC), Department of Medical Microbiology, Faculty of Medicine, University of Malay, Kuala Lumpur, Malaysia.
Seyed Farid Seyed ShiraziDepartment of Mechanical Engineering and Center of advanced Material, University of Malaya, Kuala Lumpur, Malaysia.
Saeid BaradaranDepartment of Mechanical Engineering and Center of advanced Material, University of Malaya, Kuala Lumpur, Malaysia.
Mohammad MehraliDepartment of Mechanical Engineering and Center of advanced Material, University of Malaya, Kuala Lumpur, Malaysia.
Sara Tahan LatibariDepartment of Mechanical Engineering and Center of advanced Material, University of Malaya, Kuala Lumpur, Malaysia.
Hendrik Simon Cornelis MetselaarDepartment of Mechanical Engineering and Center of advanced Material, University of Malaya, Kuala Lumpur, Malaysia.
Nahrizul Adib KadriDepartment of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia.
Keivan ZandiDepartment of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia.
Noor Azuan Abu OsmanDepartment of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium silicate (CaSiO3, CS) ceramic composites reinforced with graphene nanoplatelets (GNP) were prepared using hot isostatic pressing (HIP) at 1150°C. Quantitative microstructural analysis suggests that GNP play a role in grain size and is responsible for the improved densification. Raman spectroscopy and scanning electron microscopy showed that GNP survived the harsh processing conditions of the selected HIP processing parameters. The uniform distribution of 1 wt.% GNP in the CS matrix, high densification and fine CS grain size help to improve the fracture toughness by ∼130%, hardness by ∼30% and brittleness index by ∼40% as compared to the CS matrix without GNP. The toughening mechanisms, such as crack bridging, pull-out, branching and deflection induced by GNP are observed and discussed. The GNP/CS composites exhibit good apatite-forming ability in the simulated body fluid (SBF). Our results indicate that the addition of GNP decreased pH value in SBF. Effect of addition of GNP on early adhesion and proliferation of human osteoblast cells (hFOB) was measured in vitro. The GNP/CS composites showed good biocompatibility and promoted cell viability and cell proliferation. The results indicated that the cell viability and proliferation are affected by time and concentration of GNP in the CS matrix.

Indexed as

Biocompatible MaterialsCalcium CompoundsGraphiteNanocompositesSilicatesBiocompatible MaterialsCalcium Compoundscalcium silicateGraphiteSilicates

Identifiers

PMID25229540
PMCPMC4167702

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.