Evidence map›Paper›PMID 25229387›Full record

ReviewThe Journal of pathology2015

Molecular biology, pathogenesis and pathology of mumps virus.

Steven Rubin, Michael Eckhaus, Linda J Rennick, Connor G G Bamford, W Paul Duprex

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 236 citations in OpenAlex.

  1. Article
  2. Mumps disease and vaccination in Africa: A scoping review.Human vaccines & immunotherapeutics · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Human Riboviruses: A Comprehensive Study.Journal of molecular evolution · 2025
    Review

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Steven RubinCenter for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.
Michael Eckhaus
Linda J Rennick
Connor G G Bamford
W Paul Duprex
Boston University · USCenter for Biologics Evaluation and Research · USMRC University of Glasgow Centre for Virus Research · GBOffice of Research Services · US

Funding

Shifting a Paradigm in Vaccine Safety: From Empirical to Rational AttenuationR01AI099100 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI DUPREX, WILLIAM PAUL · 2013 to 2017
$2.0M
NIAID NIH HHS R01 AI099100NIAID NIH HHS R01 AI105063
6 · The paper itself

Abstract

Mumps is caused by the mumps virus (MuV), a member of the Paramyxoviridae family of enveloped, non-segmented, negative-sense RNA viruses. Mumps is characterized by painful inflammatory symptoms, such as parotitis and orchitis. The virus is highly neurotropic, with laboratory evidence of central nervous system (CNS) infection in approximately half of cases. Symptomatic CNS infection occurs less frequently; nonetheless, prior to the introduction of routine vaccination, MuV was a leading cause of aseptic meningitis and viral encephalitis in many developed countries. Despite being one of the oldest recognized diseases, with a worldwide distribution, surprisingly little attention has been given to its study. Cases of aseptic meningitis associated with some vaccine strains and a global resurgence of cases, including in highly vaccinated populations, has renewed interest in the virus, particularly in its pathogenesis and the need for development of clinically relevant models of disease. In this review we summarize the current state of knowledge on the virus, its pathogenesis and its clinical and pathological outcomes.

Indexed as

AnimalsBiopsyDisease Models, AnimalGenotypeHost-Pathogen InteractionsHumansMumpsMumps VaccineMumps virusPathology, MolecularPredictive Value of TestsPrognosisVirologyVirulenceMumps Vaccinemumpsmumps virusneurovirulencepathogenesisvaccine

Identifiers

PMID25229387
PMCPMC4268314
OpenAlexW1856467715

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.