ArticlePloS one2014
Results of the implementation of a pilot model for the bidirectional screening and joint management of patients with pulmonary tuberculosis and diabetes mellitus in Mexico.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effect of Tuberculosis (TB) and Diabetes mellitus (DM) integrated healthcare on bidirectional screening and treatment outcomes among TB patients and people living with DM in developing countries: a systematic review.Pathogens and global health · 2023Pooled it
- Prevalence and associated factors of tuberculosis and diabetes mellitus comorbidity: A systematic review.PloS one · 2017Pooled it
- Diabetes screening among people with tuberculosis: a systematic review and meta analysis.EClinicalMedicine · 2026Article
- Strategies to integrate non-communicable disease interventions in HIV and tuberculosis care contexts in low- and middle-income countries: a scoping review.BMJ global health · 2026Article
- Frequency of Lower Lung Field Tuberculosis in Diabetes Mellitus Patients Attending Tertiary Care Hospital in Bangladesh: A Cross-Sectional Study.Health science reports · 2025Article
- The Complex Relationship Between Tuberculosis and Hyperglycemia.Diagnostics (Basel, Switzerland) · 2024Review
- Global, regional, and national age-specific progress towards the 2020 milestones of the WHO End TB Strategy: a systematic analysis for the Global Burden of Disease Study 2021.The Lancet. Infectious diseases · 2024Article
- Prevalence of Diabetes Mellitus and its Related Factors in Patients with Tuberculosis.Archives of Iranian medicine · 2022Article
- The impact of diabetes mellitus on pulmonary TB.Public health action · 2022Article
- Bidirectional screening and treatment outcomes of diabetes mellitus (DM) and Tuberculosis (TB) patients in hospitals with measures to integrate care of DM and TB and those without integration measures in Malawi.BMC infectious diseases · 2022Article
- Implementation of the WHO's collaborative framework for the management of tuberculosis and diabetes: a scoping review.BMJ open · 2021Article
- Frontline healthcare workers' experiences in implementing the TB-DM collaborative framework in Northern Ghana.BMC health services research · 2021Article
- Barriers and facilitators to bidirectional screening of TB-DM in Ghana: Healthcare workers' perspectives.PloS one · 2020Article
- Multicenter screening of diabetic patients for detecting new cases of tuberculosis: an approach to intensify the case detection rate of tuberculosis in developing countries with high prevalence of diabetes.Journal of preventive medicine and hygiene · 2019Article
- [Co-management of tuberculosis and diabetes: an integrative reviewManejo integrado de la tuberculosis y la diabetes: revisión integrativa].Revista panamericana de salud publica = Pan American journal of public health · 2019Review
- Diabetes, undernutrition, migration and indigenous communities: tuberculosis in Chiapas, Mexico.Epidemiology and infection · 2019Article
- Prognostic factors among TB and TB/DM comorbidity among patients on short course regimen within Nairobi and Kiambu counties in Kenya.Journal of clinical tuberculosis and other mycobacterial diseases · 2018Article
- Article
- Review
- Global prevalence of diabetes mellitus in patients with tuberculosis: a systematic review and meta-analysis protocol.BMJ open · 2017Article
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecently, the World Health Organisation and the International Union Against Tuberculosis and Lung Disease published a Collaborative Framework for the Care and Control of Tuberculosis (TB) and Diabetes (DM) (CFTB/DM) proposing bidirectional screening and joint management.
objectiveTo evaluate the feasibility and effectiveness of the CFTB/DM in Mexico.
designProspective observational cohort.
setting15 primary care units in 5 states in Mexico.
participantsPatients aged ≥20 years diagnosed with DM or pulmonary TB who sought care at participating clinics.
interventionThe WHO/Union CFTB/DM was adapted and implemented according to official Mexican guidelines. We recruited participants from July 2012 to April 2013 and followed up until March 2014. Bidirectional screening was performed. Patients diagnosed with TB and DM were invited to receive TB treatment under joint management.
main outcome measuresDiagnoses of TB among DM, of DM among TB, and treatment outcomes among patients with DM and TB.
resultsOf 783 DM patients, 11 (1.4%) were unaware of their TB. Of 361 TB patients, 16 (4.4%) were unaware of their DM. 95 TB/DM patients accepted to be treated under joint management, of whom 85 (89.5%) successfully completed treatment. Multiple linear regression analysis with change in HbA1c and random capillary glucose as dependent variables revealed significant decrease with time (regression coefficients (β) = -0.660, (95% confidence interval (CI), -0.96 to -0.35); and β = -1.889 (95% CI, -2.77 to -1.01, respectively)) adjusting by sex, age and having been treated for a previous TB episode. Patients treated under joint management were more likely to experience treatment success than patients treated under routine DM and TB programs as compared to historical (adjusted OR (aOR), 2.8, 95%CI 1.28-6.13) and same period (aOR 2.37, 95% CI 1.13-4.96) comparison groups.
conclusionsJoint management of TB and DM is feasible and appears to improve clinical outcomes.
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