ArticleAllergy, asthma & immunology research2014
Capsaicin cough sensitivity is related to the older female predominant feature in chronic cough patients.
Article in Allergy, asthma & immunology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 49 citations in OpenAlex.
- Differences in Causes, Severity, and Treatment Outcomes Between Women and Men with Chronic Cough.Advances in respiratory medicine · 2026Article
- Quality of life associated with chronic cough in the multinational Burden of Obstructive Lung Disease study: a cross-sectional study.ERJ open research · 2025Article
- Treatable traits in chronic cough: a prospective evaluation for predicting cough persistence.ERJ open research · 2025Article
- Demographics, risk factors and prevalence of chronic cough in Asian general adult population: a narrative review.Journal of thoracic disease · 2025Review
- Prevalence and burden of chronic cough in China: results from a population-based survey.BMC pulmonary medicine · 2025Article
- New Insights Into Refractory Chronic Cough and Unexplained Chronic Cough: A 6-Year Ambispective Cohort Study.Allergy, asthma & immunology research · 2023Article
- Factors explaining individual differences in the oral perception of capsaicin, l-menthol, and aluminum ammonium sulfate.Clinical and translational science · 2023Article
- Patterns of Cough Medication Prescribing among Patients with Chronic Cough in Florida: 2012-2021.Journal of clinical medicine · 2023Article
- Cough Sensitivity to Several External Triggers is Associated with Multiple Non-respiratory Symptoms.Lung · 2023Article
- Environmental chamber studies of eye and respiratory irritation from use of a peracetic acid-based hospital surface disinfectant.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Characteristics of different asthma phenotypes associated with cough: a prospective, multicenter survey in China.Respiratory research · 2022Article
- Clinical and Inflammatory Characteristics of the Chinese APAC Cough Variant Asthma Cohort.Frontiers in medicine · 2021Article
- Gender Difference in Chronic Cough: Are Women More Likely to Cough?Frontiers in physiology · 2021Review
- Impact of Chronic Cough on Health-Related Quality of Life in the Korean Adult General Population: The Korean National Health and Nutrition Examination Survey 2010-2016.Allergy, asthma & immunology research · 2020Article
- Methods for assessing cough sensitivity.Journal of thoracic disease · 2020Review
- Perspectives on chronic cough in Korea.Journal of thoracic disease · 2020Review
- Cough-provocation tests with hypertonic aerosols.ERJ open research · 2020Review
- Age and Sex Distribution of Chinese Chronic Cough Patients and Their Relationship With Capsaicin Cough Sensitivity.Allergy, asthma & immunology research · 2019Article
- Cough-Related Laryngeal Sensations and Triggers in Adults With Chronic Cough: Symptom Profile and Impact.Allergy, asthma & immunology research · 2019Article
- Respiratory allergies in the elderly: findings from the Korean Longitudinal Study on Health and Aging phase I study (2005-2006).Asia Pacific allergy · 2017Review
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present study aimed to examine the age and gender distributions among chronic cough patients referred to a tertiary cough clinic in Korea, and to investigate clinical factors related to the demographic findings.
methodsStudy participants were unselectively recruited from adult chronic cough patients who attended the cough clinic for the first time during one year. To validate their representativeness, their age and gender distributions were compared to the entire chronic cough population, or with those presenting with other chronic disease. Data from the baseline investigations were analyzed to identify clinical factors related to the demographic findings.
resultsA total of 272 chronic cough patients were included. They had a middle-aged female predominant feature (mean age: 52.8±15.7 years and female 69.1%). Their age and gender distributions were almost identical to the entire chronic cough population, but were distinct from patients with hypertension. Among clinical factors, the older female predominance was associated with enhanced capsaicin cough sensitivity, and also with the presence of 'cough by cold air' symptom. Allotussia and laryngeal paresthesia were highly common in chronic cough patients, affecting 94.8% and 86.8% of them, respectively.
conclusionsThe present study demonstrated older female predominance among adult chronic cough patients attending a referral cough clinic in Korea. The demographic features were significantly associated with the capsaicin cough responses and also potentially with allotussia (particularly cold air as the trigger). These findings suggest a role of cough reflex sensitization in the pathophysiology of chronic cough in adults.
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