ReviewWorld journal of cardiology2014
Pseudoexfoliation syndrome and cardiovascular diseases.
Review in World journal of cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03373942 (Evaluation of Choroidal Thickness Using Spectral Optical Coherence Tomography in Pseudoexfoliation Glaucoma and Primary Open Angle Glaucoma), which is not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Choroidal Thickness Using Spectral Optical Coherence Tomography in Pseudoexfoliation Glaucoma and Primary Open Angle Glaucoma
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome.BMC genomics · 2023Pooled it
- Frequency, clinical characteristics and cataract surgery outcomes of pseudoexfoliation syndrome in patients with senile cataracts: a review of hospital-based data.Scientific reports · 2026Article
- Frequency of Exfoliation Syndrome Among Patients Attending an Ophthalmology Outpatient Clinic in the Northeastern Black Sea Coast of Turkey.Healthcare (Basel, Switzerland) · 2026Article
- Prevalence and associated factors of pseudoexfoliation syndrome among cataract patients attending comprehensive specialized hospitals in Northwest Ethiopia.Scientific reports · 2026Article
- Corneal endothelial and retinal microvascular changes in pseudoexfoliation syndrome: insights from specular microscopy and OCT angiography.BMC ophthalmology · 2025Article
- [High blood pressure rarely occurs alone].Die Ophthalmologie · 2025Article
- Unusual Presentation of Extensive Visually Significant Pseudoexfoliative Deposits on an Intraocular Lens Implant in a Pseudophakic Eye: Insights and Implications.Clinical optometry · 2025Article
- Hematological inflammation biomarkers in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.International journal of ophthalmology · 2025Article
- The role of serum biomarkers in determining systemic inflammation and cardiovascular risk in pseudoexfoliation syndrome.International ophthalmology · 2024Article
- Platelet Proteome Reveals Novel Targets for Hypercoagulation in Pseudoexfoliation Syndrome.International journal of molecular sciences · 2024Article
- Evaluation of serum semaphorin 3A and interleukin 6 levels in patients with pseudoexfoliation syndrome.International ophthalmology · 2023Article
- Evaluation of the segmented inner retinal layers in exfoliation glaucoma.International ophthalmology · 2023Article
- The Incident Ocular Diseases Related to Chemotherapy in Cancer Patients are Associated with Increasing Risk of Incident Stroke.Acta Cardiologica Sinica · 2023Article
- Results of Nailfold Videocapillaroscopy in Patients with Pseudoexfoliative Glaucoma.Life (Basel, Switzerland) · 2023Article
- Review
- Article
- Exfoliation Syndrome in Baja Verapaz Guatemala: A Cross-Sectional Study and Review of the Literature.Journal of clinical medicine · 2022Article
- Risk factors for fluctuations in corneal endothelial cell density (Review).Experimental and therapeutic medicine · 2022Review
- Sectorwise analysis of peripapillary vessel density and retinal nerve fiber layer thickness in exfoliation syndrome.International ophthalmology · 2021Article
- Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pseudoexfoliation (PEX) syndrome is a well-recognized late-onset disease caused by a generalized fibrillopathy. It is linked to a broad spectrum of ocular complications including glaucoma and perioperative problems during cataract surgery. Apart from the long-known intraocular manifestations, PEX deposits have been found in a variety of extraocular locations and they appear to represent a systemic process associated with increased cardiovascular and cerebrovascular morbidity. However, as published results are inconsistent, the clinical significance of the extraocular PEX deposits remains controversial. Identification of PEX deposits in the heart and the vessel wall, epidemiologic studies, as well as, similarities in pathogenetic mechanisms have led to the hypothesis of a possible relation between fibrillar material and cardiovascular disease. Recent studies suggest that PEX syndrome is frequently linked to impaired heart and blood vessels function. Systemic and ocular blood flow changes, altered parasympathetic vascular control and baroreflex sensitivity, increased vascular resistance and decreased blood flow velocity, arterial endothelial dysfunction, high levels of plasma homocysteine and arterial hypertension have all been demonstrated in PEX subjects. Common features in the pathogenesis of both atherosclerosis and PEX, like oxidative stress and inflammation and a possible higher frequency of abdominal aorta aneurysm in PEX patients, could imply that these grey-white deposits and cardiovascular disorders are related or reflect different manifestations of the same process.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.