Evidence map›Paper›PMID 25228955›Full record

ReviewWorld journal of cardiology2014

Hypertrophic cardiomyopathy: Can the noninvasive diagnostic testing identify high risk patients?

Li Zhang, Obinna Mmagu, Liwen Liu, Dayuan Li, Yuxin Fan, Adrian Baranchuk, Peter R Kowey

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Li ZhangLi Zhang, Obinna Mmagu, Peter R Kowey, Center for Clinical Cardiology, Lankenau Institute for Medical Research, Lankenau Medical Center, Jefferson Medical College, Philadelphia, PA 19096, United States.
Obinna MmaguLi Zhang, Obinna Mmagu, Peter R Kowey, Center for Clinical Cardiology, Lankenau Institute for Medical Research, Lankenau Medical Center, Jefferson Medical College, Philadelphia, PA 19096, United States.
Liwen LiuLi Zhang, Obinna Mmagu, Peter R Kowey, Center for Clinical Cardiology, Lankenau Institute for Medical Research, Lankenau Medical Center, Jefferson Medical College, Philadelphia, PA 19096, United States.
Dayuan LiLi Zhang, Obinna Mmagu, Peter R Kowey, Center for Clinical Cardiology, Lankenau Institute for Medical Research, Lankenau Medical Center, Jefferson Medical College, Philadelphia, PA 19096, United States.
Yuxin FanLi Zhang, Obinna Mmagu, Peter R Kowey, Center for Clinical Cardiology, Lankenau Institute for Medical Research, Lankenau Medical Center, Jefferson Medical College, Philadelphia, PA 19096, United States.
Adrian BaranchukLi Zhang, Obinna Mmagu, Peter R Kowey, Center for Clinical Cardiology, Lankenau Institute for Medical Research, Lankenau Medical Center, Jefferson Medical College, Philadelphia, PA 19096, United States.
Peter R KoweyLi Zhang, Obinna Mmagu, Peter R Kowey, Center for Clinical Cardiology, Lankenau Institute for Medical Research, Lankenau Medical Center, Jefferson Medical College, Philadelphia, PA 19096, United States.
Lankenau Institute for Medical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden cardiac death (SCD) in the young, particularly among athletes. Identifying high risk individuals is very important for SCD prevention. The purpose of this review is to stress that noninvasive diagnostic testing is important for risk assessment. Extreme left ventricular hypertrophy and documented ventricular tachycardia and fibrillation increase the risk of SCD. Fragmented QRS and T wave inversion in multiple leads are more common in high risk patients. Cardiac magnetic resonance imaging provides complete visualization of the left ventricular chamber, allowing precise localization of the distribution of hypertrophy and measurement of wall thickness and cardiac mass. Moreover, with late gadolinium enhancement, patchy myocardial fibrosis within the area of hypertrophy can be detected, which is also helpful in risk stratification. Genetic testing is encouraged in all cases, especially in those with a family history of HCM and SCD.

Indexed as

Hypertrophic cardiomyopathyNoninvasive diagnostic testingSudden cardiac death

Identifiers

PMID25228955
PMCPMC4163705
OpenAlexW1990361646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.