ArticleFrontiers in behavioral neuroscience2014
A controlled study on the cognitive effect of alpha neurofeedback training in patients with major depressive disorder.
Article in Frontiers in behavioral neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Resting-state EEG activity in depression: a systematic review and meta-analysis.NeuroImage. Clinical · 2026Pooled it
- Neuroimaging Insights into the Public Health Burden of Neuropsychiatric Disorders: A Systematic Review of Electroencephalography-Based Cognitive Biomarkers.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Review of EEG-based neurofeedback as a therapeutic intervention to treat depression.Psychiatry research. Neuroimaging · 2023Pooled it
- Efficacy of Neuro-Feedback Training for PTSD Symptoms: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Efficacy of bio- and neurofeedback for depression: a meta-analysis.Psychological medicine · 2022Pooled it
- Individual variation in alpha neurofeedback training efficacy predicts pain modulation.NeuroImage. Clinical · 2020Trial
- A quick behavioral dichotic word test is prognostic for clinical response to cognitive therapy for depression: A replication study.Psychiatry research · 2017Trial
- Specific effects of EEG based neurofeedback training on memory functions in post-stroke victims.Journal of neuroengineering and rehabilitation · 2015Trial
- [Neuromodulation as the fourth pillar in the treatment of depression : A position paper of the German Center for Mental Health].Der Nervenarzt · 2026Review
- EEG Neurofeedback for Major Depressive Disorder: A Scoping Review.Alpha psychiatry · 2026Review
- Parietal gamma oscillations decreased in cognitive biotype of depression.Scientific reports · 2025Article
- Neural oscillations induced by gamma sensory entrainment in cognitive biotype of depression.Frontiers in psychiatry · 2025Article
- Alpha neurofeedback training improves visual working memory in healthy individuals.NPJ science of learning · 2024Article
- The Role of Alpha Oscillations among the Main Neuropsychiatric Disorders in the Adult and Developing Human Brain: Evidence from the Last 10 Years of Research.Biomedicines · 2022Review
- The Current Evidence Levels for Biofeedback and Neurofeedback Interventions in Treating Depression: A Narrative Review.Neural plasticity · 2021Review
- Affective Neurofeedback Under Naturalistic Conditions: A Mini-Review of Current Achievements and Open Challenges.Frontiers in neuroergonomics · 2021Review
- A Neurofeedback Protocol for Executive Function to Reduce Depression and Rumination: A Controlled Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2020Article
- The role of the subgenual anterior cingulate cortex in dorsomedial prefrontal-amygdala neural circuitry during positive-social emotion regulation.Human brain mapping · 2020Article
- Why Brain Criticality Is Clinically Relevant: A Scoping Review.Frontiers in neural circuits · 2020Article
- Neurofeedback in ADHD: A qualitative study of strategy use in slow cortical potential training.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cognitive deficits are core symptoms of depression. This study aims to investigate whether neurofeedback (NF) training can improve working memory (WM) performance in patients with major depressive disorder (MDD). The NF group (n = 40) underwent eight NF sessions and was compared to a non-interventional control group (n = 20). The NF protocol aimed to increase the individual upper alpha power in the parieto-occipital area of the scalp. Main cognitive variable was WM, which was measured pre- and post- training along with other variables such as attention and executive functions. EEG was recorded in both eyes closed resting state and eyes open task-related activity, pre- and post- NF training, and pre- and post- the NF trials within each session. A power EEG analysis and an alpha asymmetry analysis were conducted at the sensor level. Frequency domain standardized low resolution tomography (sLORETA) was used to assess the effect at brain source level. Correlation analysis between the clinical/cognitive and EEG measurements was conducted at both the sensor and brain source level. The NF group showed increased performance as well as improved processing speed in a WM test after the training. The NF group showed pre-post enhancement in the upper alpha power after the training, better visible in task-related activity as compared to resting state. A current density increase appeared in the alpha band (8-12 Hz) for the NF group, localized in the subgenual anterior cingulate cortex (sgACC, BA 25). A positive correlation was found for the NF group between the improvement in processing speed and the increase of beta power at both the sensor and brain source level. These results show the effectiveness of this NF protocol in improving WM performance in patients with MDD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.