ReviewMolecular imaging and biology2015
Hyperpolarized and inert gas MRI: the future.
Review in Molecular imaging and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02748798 (Developing Optimal Parameters for Hyperpolarized Noble Gas), which is not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Developing Optimal Parameters for Hyperpolarized Noble Gas (3He and 129Xe) and Inert Fluorinated Gas Magnetic Resonance Imaging of Lung Disorders
Who cites it
20 citing papers in PubMed.
- Evaluation of Resorcinarene Trimer Methanesulfonate Aggregation in the Presence of Inorganic Salts and Biomolecules in Aqueous Solutions Using UV-vis Spectroscopy and Electrophoresis.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026Article
- UltrasensitiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Hyperpolarized Xenon-129 Chemical Exchange Saturation Transfer (HyperCEST) Molecular Imaging: Achievements and Future Challenges.International journal of molecular sciences · 2024Review
- Hyperpolarized Carbon 13 MRI: Clinical Applications and Future Directions in Oncology.Radiology. Imaging cancer · 2023Review
- HyperpolarizedMagnetic resonance in medicine · 2022Review
- HyperpolarizedAcademic radiology · 2022Article
- Evaluation of fluorine-19 magnetic resonance imaging of the lungs using octafluorocyclobutane in a rat model.Magnetic resonance in medicine · 2021Article
- Paramagnetic Organocobalt Capsule Revealing Xenon Host-Guest Chemistry.Inorganic chemistry · 2020Article
- Paramagnetic Shifts and Guest Exchange Kinetics in CoInorganic chemistry · 2020Article
- Perfluorocarbons-BasedInternational journal of nanomedicine · 2020Review
- Optimization of steady-state free precession MRI for lung ventilation imaging withMagnetic resonance in medicine · 2019Article
- A Structural Basis forChemphyschem : a European journal of chemical physics and physical chemistry · 2019Article
- Nanoparticle-Based Contrast Agents forContrast media & molecular imaging · 2019Review
- Pulmonary ventilation imaging in asthma and cystic fibrosis using oxygen-enhanced 3D radial ultrashort echo time MRI.Journal of magnetic resonance imaging : JMRI · 2018Article
- Hyperpolarized carbon-13 magnetic resonance spectroscopic imaging: a clinical tool for studying tumour metabolism.The British journal of radiology · 2018Review
- Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production byBioorganic & medicinal chemistry · 2017Article
- HyperpolarizedJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2017Article
- Imaging of Brown Adipose Tissue: State of the Art.Radiology · 2016Review
- Fluorine-19 MRI Contrast Agents for Cell Tracking and Lung Imaging.Magnetic resonance insights · 2015Review
- Optically polarizedReviews of modern physicsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnetic resonance imaging (MRI) is a potentially ideal imaging modality for noninvasive, nonionizing, and longitudinal assessment of disease. Hyperpolarized (HP) agents have been developed in the past 20 years for MR imaging, and they have the potential to vastly improve MRI sensitivity for the diagnosis and management of various diseases. The polarization of nuclear magnetic resonance (NMR)-sensitive nuclei other than (1)H (e.g., (3)He, (129)Xe) can be enhanced by a factor of up to 100,000 times above thermal equilibrium levels, which enables direct detection of the HP agent with no background signal. In this review, a number of HP media applications in MR imaging are discussed, including HP (3)He and (129)Xe lung imaging, HP (129)Xe brain imaging, and HP (129)Xe biosensors. Inert fluorinated gas MRI, which is a new lung imaging technique that does not require hyperpolarization, is also briefly discussed. This technique will likely be an important future direction for the HP gas lung imaging community.
Indexed as
Identifiers
25228404What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.