ArticleJournal of assisted reproduction and genetics2014
Association of IL-17A and IL-17 F gene polymorphisms with recurrent pregnancy loss in Iranian women.
Article in Journal of assisted reproduction and genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Association ofInternational journal of fertility & sterility · 2023Pooled it
- Association of IL-17 and IL-27 polymorphisms with susceptibility to recurrent pregnancy loss and pre-eclampsia: A systematic review and meta-analysis.Immunity, inflammation and disease · 2023Pooled it
- Genetic polymorphisms of IL-17A rs2275913, rs3748067 and IL-17F rs763780 in gastric cancer risk: evidence from 8124 cases and 9873 controls.Molecular biology reports · 2018Pooled it
- Association between Genetic Polymorphisms in Interleukin Genes and Recurrent Pregnancy Loss - A Systematic Review and Meta-Analysis.PloS one · 2017Pooled it
- The association of IL-17A rs2275913 single nucleotide polymorphism with anti-tuberculous drug resistance in patients with pulmonary tuberculosis.Journal, genetic engineering & biotechnology · 2023Article
- Recurrent Abortion and the Involvement of Killer-Cell Immunoglobulin-like Receptor (KIR) Genes, Activated T Cells, NK Abnormalities, and Cytokine Profiles.Journal of clinical medicine · 2023Review
- Association of cytotoxic T-lymphocyte-associated protein 4 polymorphisms with recurrent pregnancy loss: A case-control study.International journal of reproductive biomedicine · 2023Article
- Immunogenetic Role of IL17A Polymorphism in the Pathogenesis of Recurrent Miscarriage.Journal of clinical medicine · 2022Article
- CD4Epigenetics · 2022Article
- Article
- TheInternational journal of women's health · 2021Article
- Physiological and pathological regulation of autophagy in pregnancy.Archives of gynecology and obstetrics · 2020Review
- Association between the TOX3 rs3803662 C>T polymorphism and recurrent miscarriage in a southern Chinese population.Journal of clinical laboratory analysis · 2019Article
- Genetics of recurrent pregnancy loss among Iranian population.Molecular genetics & genomic medicine · 2019Review
- Advances in Understanding the Immune Imbalance between T-Lymphocyte Subsets and NK Cells in Recurrent Spontaneous Abortion.Geburtshilfe und Frauenheilkunde · 2018Article
- DNA methyltransferase 3A promoter polymorphism is associated with the risk of human spontaneous abortion after assisted reproduction techniques and natural conception.Journal of assisted reproduction and genetics · 2017Article
- The IL-6 -634C/G polymorphism: a candidate genetic marker for the prediction of idiopathic recurrent pregnancy loss.International journal of reproductive biomedicine · 2016Article
- Genetic Analysis of IL-17 Gene Polymorphisms in Gout in a Male Chinese Han Population.PloS one · 2016Article
- Interleukin-17 and leptin genes polymorphisms and their levels in relation to recurrent pregnancy loss in Egyptian females.Immunogenetics · 2015Article
- The association between single nucleotide polymorphism in interleukin-27 gene and recurrent pregnancy loss in Iranian women.Iranian journal of reproductive medicine · 2015Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRecurrent pregnancy loss (RPL) is defined as the occurrence of two or more miscarriages before the 20th week of pregnancy. T helper17 cells are a novel subset of T cells, which secrete IL (Interleukin)-17 and are known to be involved in inflammation, autoimmunity and rejection of non-self tissues. Herein, we studied the association between IL-17A rs2275913 and IL-17F rs763780 gene polymorphisms with RPL in Iranian women.
methodsA case-controlled study was performed on two groups consisting of 85 healthy women with at least one delivery and 85 women with the history of two or more RPLs. The frequency of IL-17A rs2275913 and IL-17 F rs763780 polymorphisms were determined by PCR-RFLP.
resultsIn the RPL group, the genotypes frequencies of rs2275913 polymorphism were GG (8.2 %), AG (30.6 %), and AA (61.2 %) and in the control group, were GG (3.5 %), AG (42.4 %) and AA (54.1 %). Statistical analysis showed no significant difference between the genotypes of AA, AG and GG in the two groups (p = 0.1). The genotypes frequencies of rs763780 polymorphism were TT (43.5 %), TC (49.4 %) and CC (7.1 %) in the RPL group; whereas the frequencies were TT (25.9 %), TC (70.6 %) and CC (3.5 %) in the control group. Statistical analysis revealed a significant difference in the TT, TC, and CC genotypes frequencies between the case and the control groups (p = 0.01).
conclusionsOur findings indicate that IL-17F polymorphism, rs763780, might be associated with a high risk of RPL in Iranian women.
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