ArticlemBio2014
An epistemological perspective on the value of gain-of-function experiments involving pathogens with pandemic potential.
Article in mBio, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Biosafety, biosecurity, and bioethics.Monash bioethics review · 2024Review
- Grand challenge in biosafety and biosecurity.Frontiers in bioengineering and biotechnology · 2024Article
- Article
- Why Do Exceptionally Dangerous Gain-of-Function Experiments in Influenza?Methods in molecular biology (Clifton, N.J.) · 2018Review
- The Silver Lining in Gain-of-Function Experiments with Pathogens of Pandemic Potential.Methods in molecular biology (Clifton, N.J.) · 2018Review
- Ethical and Philosophical Considerations for Gain-of-Function Policy: The Importance of Alternate Experiments.Frontiers in bioengineering and biotechnology · 2018Article
- Gain-of-Function Research: Ethical Analysis.Science and engineering ethics · 2016Article
- Infectious Diseases Society of America and Gain-of-Function Experiments With Pathogens Having Pandemic Potential.The Journal of infectious diseases · 2016Article
- Transformed Recombinant Enrichment Profiling Rapidly Identifies HMW1 as an Intracellular Invasion Locus in Haemophilus influenza.PLoS pathogens · 2016Article
- Fitness Inference from Short-Read Data: Within-Host Evolution of a Reassortant H5N1 Influenza Virus.Molecular biology and evolution · 2015Article
- The ethics of biosafety considerations in gain-of-function research resulting in the creation of potential pandemic pathogens.Journal of medical ethics · 2015Article
- Article
- A new synthesis for dual use research of concern.PLoS medicine · 2015Article
- Gain-of-function experiments: time for a real debate.Nature reviews. Microbiology · 2015Review
- Article
- Article
- Article
- Article
- Article
- Can limited scientific value of potential pandemic pathogen experiments justify the risks?mBio · 2014Article
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
- Commented on by
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.