Evidence map›Paper›PMID 25227281›Full record

ArticleEuropean journal of pediatrics2015

Nasal high-frequency oscillation ventilation in neonates: a survey in five European countries.

Hendrik Stefan Fischer, Kajsa Bohlin, Christoph Bührer, Gerd Schmalisch, Malte Cremer, Irwin Reiss, Christoph Czernik

3 registry-linked trialsOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in European journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 28 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 11 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02543125 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Nasal High Frequency Oscillatory Versus Nasal Intermittent Positive Pressure Ventilation in Neonate After Extubation

TypeinterventionalSponsorGao WeiWeiRan2016 to 2016Enrolled75ConditionsRespiratory InsufficiencyArmsNIPPV, NHFOV
NCT03006354 nacompletednot on this mapstarted 2017, after this paper: background citation

Nasal High Frequency Oscillatory Ventilation Versus Nasal Continuous Positive Airway Pressure in Late-Preterm and Term Infants With Transient Tachypnea of the Newborn: a Randomized Controlled Trial

TypeinterventionalSponsorThe Hospital for Sick ChildrenRan2017 to 2018Enrolled60ConditionsTransient Tachypnea of the NewbornArmsnHFOV, nCPAP
NCT04914715 nawithdrawnnot on this mapstarted 2021, after this paper: background citation

Effectiveness of Non-invasive High Frequency Oscillatory Ventilation (nHFOV) Versus Invasive Conventional Ventilation for Preterm Neonates With Respiratory Distress Syndrome

TypeinterventionalSponsorIndus Hospital and Health NetworkRan2021 to 2023Enrolled0ConditionsRespiratory Distress Syndrome in Premature InfantArmsNon-invasive High Frequency Oscillatory Ventilation, Conventional Invasive Ventilation
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 11 syntheses or guidelines pooled it, 96 citations in OpenAlex.

  1. Pooled it
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  3. Peri-extubation settings in preterm neonates: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2024
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  6. Guideline
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  11. Sustained inflations and avoiding mechanical ventilation to prevent death or bronchopulmonary dysplasia: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2018
    Pooled it
  12. Trial
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  20. [Prospects and developments in the technologies of high frequency oscillatory ventilation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Hendrik Stefan FischerDepartment of Neonatology, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany, hendrik.fischer@charite.de.
Kajsa Bohlin
Christoph Bührer
Gerd Schmalisch
Malte Cremer
Irwin Reiss
Christoph Czernik
Charité - Universitätsmedizin Berlin · DEErasmus MC - Sophia Children’s Hospital · NLKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledNasal high-frequency oscillation ventilation (nHFOV) is a non-invasive ventilation mode that applies an oscillatory pressure waveform to the airways using a nasal interface. nHFOV has been shown to facilitate carbon dioxide expiration, but little is known about its use in neonates. In a questionnaire-based survey, we assessed nHFOV use in neonatal intensive care units (NICUs) in Austria, Switzerland, Germany, the Netherlands, and Sweden. Questions included indications for nHFOV, equipment used, ventilator settings, and observed side effects. Of the clinical directors of 186 NICUs contacted, 172 (92 %) participated. Among those responding, 30/172 (17 %) used nHFOV, most frequently in premature infants <1500 g (27/30) for the indication nasal continuous positive airway pressure (nCPAP) failure (27/30). Binasal prongs (22/30) were the most common interfaces. The median (range) mean airway pressure when starting nHFOV was 8 (6-12) cm H2O, and the maximum mean airway pressure was 10 (7-18) cm H2O. The nHFOV frequency was 10 (6-13) Hz. Abdominal distension (11/30), upper airway obstruction due to secretions (8/30), and highly viscous secretions (7/30) were the most common nHFOV side effects.

conclusionIn a number of European NICUs, clinicians use nHFOV. The present survey identified differences in nHFOV equipment, indications, and settings. Controlled clinical trials are needed to investigate the efficacy and side effects of nHFOV in neonates.

Indexed as

AustriaContinuous Positive Airway PressureGermanyHigh-Frequency VentilationHumansInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalNetherlandsNoninvasive VentilationSurveys and QuestionnairesSwedenSwitzerland

Identifiers

PMID25227281
OpenAlexW2162870665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.