Evidence map›Paper›PMID 25227210›Full record

ArticleHead & neck2016

Race disparities attributed to volumetric tumor burden in patients with head and neck cancer treated with radiotherapy.

Muhammad M Qureshi, Paul B Romesser, Abdallah Ajani, Lisa A Kachnic, Scharukh Jalisi, Minh Tam Truong

Abstract readComparative Study
In one paragraph

Article in Head & neck, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The prognosis and treatment of newly diagnosed bone metastasis of head and neck squamous cell cancer: an analysis of racial disparity.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muhammad M QureshiDepartment of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.
Paul B RomesserDepartment of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.
Abdallah AjaniDepartment of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.
Lisa A KachnicDepartment of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.
Scharukh JalisiDepartment of Otolaryngology, Division of Head and Neck Surgical Oncology and Skull Base Surgery, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.
Minh Tam TruongDepartment of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundThe purpose of this study was to evaluate how gross tumor volume (GTV) affects treatment outcome among different race/ethnic groups in patients with head and neck cancer receiving definitive radiotherapy (RT).

methodsNinety-one patients with head and neck cancer were treated to a median RT dose of 69.96 Gy in 33 fractions. The patient's self-reported race/ethnicity, primary tumor, and nodal GTV were obtained. Two-year actuarial local, nodal, and distant control, and overall and disease-free survival were calculated.

resultsThe patients were categorized as white (n = 43) or non-white (n = 48), which included 29 African Americans, 11 Hispanics, 5 Asians, and 3 others. The mean primary GTV was 21.0 cc and 39.9 cc for whites and non-whites, respectively (p = .011). White patients reported improved overall survival of 85.4% compared to non-whites (65.8%; p = .006). Improvements in local and nodal control and disease-free survival rates were also observed.

conclusionWhite patients demonstrated improved treatment outcomes compared with non-whites, which may be reflective of tumor volume.

Indexed as

AgedAsianBlack or African AmericanCarcinoma, Squamous CellDisease-Free SurvivalFemaleFollow-Up StudiesHead and Neck NeoplasmsHispanic or LatinoHumansMaleMiddle AgedNeoplasm StagingRadiotherapy, ConformalRadiotherapy DosageRetrospective Studiesethnicitygross tumor volumehead and neck cancerraceradiotherapy

Identifiers

PMID25227210
PMCPMC5018051

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.