ArticlePediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2014
An epidemiologic survey of pediatric sepsis in regional hospitals in China.
Article in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Pathogenic spectrum, antibiotic resistance, and risk factors for 28-day mortality in pediatric bloodstream infection-associated sepsis: a 10-year retrospective cohort study.Microbiology spectrum · 2026Article
- Predictive Value of Cardiac Troponin Combined with p-SOFA Score in Sepsis Children with PCIS ≥ 70.International journal of general medicine · 2026Article
- Risk factors for 28-day mortality and pathogen characteristics of septic shock in children: a 10-year retrospective cohort study.Frontiers in cellular and infection microbiology · 2026Article
- Prevalence and clinical impact of Vitamin A Deficiency (VAD) in critically ill children with sepsis.BMC pediatrics · 2025Article
- Plasma proteomics in pediatric patients with sepsis- hopes and challenges.Clinical proteomics · 2025Review
- Risk factors associated with mortality and pathogen characteristics of bloodstream infection-induced severe sepsis in the pediatric intensive care unit: a retrospective cohort study.Frontiers in cellular and infection microbiology · 2025Article
- A randomized controlled trial on the efficacy and safety of vitamin A supplementation in children with sepsis.Frontiers in pediatrics · 2025Article
- Metabolomic Profiling by UPLC-QTOF/MS Reveals Potential Biomarkers and Metabolic Alterations in Pediatric Septic Shock.Journal of inflammation research · 2025Article
- Article
- Alanine, a potential amino acid biomarker of pediatric sepsis: a pilot study in PICU.Amino acids · 2024Article
- The Role of Soluble Urokinase Plasminogen Activator Receptor (suPAR) as an Early Indicator of Mortality in Pediatric Septic Shock.Journal of clinical laboratory analysis · 2024Article
- Effects of integrated blood purification on haemodynamics and oxygen metabolism in children with severe sepsis.Frontiers in medicine · 2024Article
- Sepsis heterogeneity.World journal of pediatrics : WJP · 2023Review
- Epidemiology and clinical characteristics of pediatric sepsis in PICUs of China: A national cross-sectional study.MedComm · 2023Article
- Refining empiric subgroups of pediatric sepsis using machine-learning techniques on observational data.Frontiers in pediatrics · 2023Review
- Comparison between hospital- and community-acquired septic shock in children: a single-center retrospective cohort study.World journal of pediatrics : WJP · 2022Article
- Effect of fluid load on the prognosis of children with sepsis-associated acute kidney injury undergoing continuous renal replacement therapy.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- Association of mitochondrial respiratory chain enzymes with the risk and mortality of sepsis among Chinese children.BMC infectious diseases · 2022Article
- LNC-ZNF33B-2:1 gene rs579501 polymorphism is associated with organ dysfunction and death risk in pediatric sepsis.Frontiers in genetics · 2022Article
- Epidemiology of pediatric sepsis in the pediatric intensive care unit of king Abdulaziz Medical City, Jeddah, Saudi Arabia.BMC pediatrics · 2021Article
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the prevalence, treatment, and outcomes of sepsis at regional hospitals in Huai'an, Jiangsu, China.
designProspective data registry using a descriptive clinical epidemiologic approach through a collaborative network.
settingPediatric departments in 11 regional city and county referral hospitals serving 843,000 children (exclusive of neonates). SUBJECTS: All admissions (n = 27,836) of patients from 28 days to 15 years old from September 1, 2010, to August 31, 2011.
interventionsNone. MEASUREMENTS AND MAIN
resultsA total of 1,530 patients met the 2005 international consensus definition of sepsis, corresponding to an estimated incidence of 181/100,000 children, with 80% under 5 years old, and in 10% (153), severe sepsis or septic shock developed. The overall case fatality rate for sepsis was 3.5% (53/1,530) or 34.6% (53/153) in those in whom severe sepsis or septic shock developed. Treatment varied widely and in many instances did not conform to international guidelines as reflected by inadequate use of antibiotics, corticosteroids, vasoactive agents, and inotropes.
conclusionsWe first report the prevalence and outcome of pediatric sepsis based on a regional hospital network in China. The diverse treatment approaches and practice at low-level clinics suggest the need for clinical implementation of internationally recognized strategy to improve the care standard in resource-limited regional hospitals.
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