Evidence map›Paper›PMID 25226168›Full record

ArticlePloS one2014

Anxiety and depression mediate the health-related quality of life differently in patients with cardiovascular disease and stroke-preliminary report of the Yilan study: a population-based community health survey.

Nai-Wei Hsu, Hsuan-Ming Tsao, Hsi-Chung Chen, Pesus Chou

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

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  5. Volunteering and self-reported health outcomes among older people living in the community: the Yilan study, Taiwan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Nai-Wei HsuDivision of Cardiology, Department of Internal Medicine, National Yang-Ming University Hospital, Yilan, Taiwan; Department of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Community Medicine Research Center & Institute of Public Health, National Yang-Ming University, Taipei, Taiwan.
Hsuan-Ming TsaoDivision of Cardiology, Department of Internal Medicine, National Yang-Ming University Hospital, Yilan, Taiwan; Department of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Hsi-Chung ChenDepartment of Psychiatry and Center of Sleep Disorders, National Taiwan University Hospital, Taipei, Taiwan.
Pesus ChouCommunity Medicine Research Center & Institute of Public Health, National Yang-Ming University, Taipei, Taiwan.
National Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TWNational Yang Ming Chiao Tung University · TWNational Yang Ming University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease and stroke have emerged as substantial and growing health challenges to populations around the world. Besides for the survival and medical prognosis, how to improve the health-related quality of life (HRQoL) might also become one of the goals of treatment programs. There are multiple factors that influence HRQol, including comorbidity, mental function and lifestyle. However, substantial research and investigation have still not clarified these underlying pathways, which merit further attention. The purpose of this study was to determine how psychological factors affect the link between cardiovascular disease and stroke with HRQoL. METHODS AND

resultA total of 1,285 elder subjects at least 65 years of age (47.2% male) were enrolled. The mental function and HRQol of each patient was then measured using the Hospital Anxiety and Depression Scale and Short Form-12. After multiple regression analysis, anxiety, depression, cardiovascular disease, stroke, education level and age were shown to be associated with both mental component score (MCS) and physical component score (PCS). In the mediation analysis using the SPSS macro provided by Preacher and Hayes, cardiovascular disease and stroke affected HRQoL via anxiety and depression, respectively.

conclusionsThese results suggest that cardiovascular disease and stroke have negative impacts on patient MCS and PCS through different underlying pathways. Cardiovascular disease influences the HRQoL both directly and indirectly with the mediation of anxiety, and stroke influences the HRQoL by way of depression. These findings support the proposition that different combinations of both physical and psychological support are necessary to best manage these diseases.

Indexed as

AnxietyDepressionQuality of LifeAgedAged, 80 and overCardiovascular DiseasesFemaleHumansMalePublic Health SurveillanceRisk FactorsStroke

Identifiers

PMID25226168
PMCPMC4166664
OpenAlexW2065487351

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.