Evidence map›Paper›PMID 25225633›Full record

ArticlePhotoacoustics2014

Cellulose Nanoparticles are a Biodegradable Photoacoustic Contrast Agent for Use in Living Mice.

Jesse V Jokerst, Dominique Van de Sompel, Sarah E Bohndiek, Sanjiv S Gambhir

Abstract read
In one paragraph

Article in Photoacoustics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  8. Review
  9. Molecular Imaging in Nanotechnology and Theranostics.Molecular imaging and biology · 2017
    Review
  10. Review
  11. What is new in nanoparticle-based photoacoustic imaging?Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2017
    Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jesse V JokerstMolecular Imaging Program at Stanford (MIPS), Department of Radiology, 318 Campus Drive, Stanford University Stanford, CA 94305-5427, .
Dominique Van de SompelMolecular Imaging Program at Stanford (MIPS), Department of Radiology, 318 Campus Drive, Stanford University Stanford, CA 94305-5427, .
Sarah E BohndiekMolecular Imaging Program at Stanford (MIPS), Department of Radiology, 318 Campus Drive, Stanford University Stanford, CA 94305-5427, .
Sanjiv S GambhirMolecular Imaging Program at Stanford (MIPS), Department of Radiology, 318 Campus Drive, Stanford University Stanford, CA 94305-5427, , ; Bioengineering, Materials Science & Engineering, Bio-X Stanford University, Stanford, CA 94305.

Funding

Small Animal ImagingP50CA114747 · NCI · STANFORD UNIVERSITY · PI RAO, JIANGHONG · 2005 to 2014
$18.2M
Pilot ProjectsU54CA151459 · NCI · STANFORD UNIVERSITY · PI RAO, JIANGHONG · 2010 to 2014
$12.6M
Stanford Molecular Imaging Scholars - SMISR25CA118681 · NCI · STANFORD UNIVERSITY · PI LEVIN, CRAIG S · 2006 to 2015
$5.0M
NCI NIH HHS P50 CA114747NCI NIH HHS R25 CA118681NCI NIH HHS U54 CA151459
6 · The paper itself

Abstract

Molecular imaging with photoacoustic ultrasound is an emerging field that combines the spatial and temporal resolution of ultrasound with the contrast of optical imaging. However, there are few imaging agents that offer both high signal intensity and biodegradation into small molecules. Here we describe a cellulose-based nanoparticle with peak photoacoustic signal at 700 nm and an

Indexed as

biodegradable nanoparticlebiodegradationcellulosenanoparticleoptoacousticovarian cancerPhotoacoustic imaging

Identifiers

PMID25225633
PMCPMC4161983

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.