ArticleJournal of experimental botany2015
Comparative physiological, metabolomic, and transcriptomic analyses reveal mechanisms of improved abiotic stress resistance in bermudagrass [Cynodon dactylon (L). Pers.] by exogenous melatonin.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers, 1 of them a synthesis that pooled it.
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Who cites it
186 citing papers in PubMed, 1 synthesis or guideline pooled it, 549 citations in OpenAlex.
- Melatonin Induced Cold Tolerance in Plants: Physiological and Molecular Responses.Frontiers in plant science · 2022Pooled it
- Osmotic stress and melatonin in Pfaffia glomerata: biochemical responses and 20-hydroxyecdysone modulation.Protoplasma · 2026Article
- Inhibitory Effect of Melatonin on the Proliferation of Breast Cancer Cells MDA-MB-468 by Antioxidants Superoxide Dismutase and Glutathione Peroxidase.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- The regulatory roles of flavonoids, melatonin, and glycine betaine in plant salt stress response.Frontiers in plant science · 2026Review
- Harnessing foliar-applied melatonin to improve yield and stress tolerance in tomato (Frontiers in plant science · 2026Article
- Exogenous plant growth regulators alleviate natural high temperature stress after anthesis in wheat (Frontiers in plant science · 2026Article
- Crosstalk between glutathione and melatonin in chromium detoxification in sweet potato revealed by high-throughput sequencing and physio-biochemical profiling.Frontiers in plant science · 2026Article
- SlWRKY6-dependent melatonin signaling regulates photosynthesis to confer cold tolerance in tomato.Plant cell reports · 2025Article
- Review
- Melatonin Enhances Drought Tolerance by Regulating the Genes Underlying Photosynthesis and Antioxidant Defense in Rubber Tree (Plants (Basel, Switzerland) · 2025Article
- Assessment of Seed Priming With Melatonin to Improve Morpho-Physiological and Biochemical Aspects of Common Bean (Plant direct · 2025Article
- Phyllospheric application of Bacillus mucilaginosus mediates the recovery of tea plants exposed to low-temperature stress by alteration of leaf endophytic community and plant physiology.BMC microbiology · 2025Article
- Article
- Melatonin application alleviates adverse effects of low light on tobacco seedlings via enhancing antioxidant and carbohydrate metabolism.Frontiers in plant science · 2025Article
- Epibrassinolide and melatonin co-treatment enhances salt tolerance in tomato plants by coordinating photosynthetic efficiency, proline accumulation, and antioxidant defense.Frontiers in plant science · 2025Article
- Melatonin-Mediated Modulation of Grapevine Resistance Physiology, Endogenous Hormonal Dynamics, and Fruit Quality Under Varying Irrigation Amounts.International journal of molecular sciences · 2024Article
- Regulation of Plant Growth and Development by Melatonin.Life (Basel, Switzerland) · 2024Review
- Melatonin: dual players mitigating drought-induced stress in tomatoes via modulation of phytohormones and antioxidant signaling cascades.BMC plant biology · 2024Article
- Role of Neurotransmitters (Biomediators) in Plant Responses to Stress.Plants (Basel, Switzerland) · 2024Review
- Enhancing drought stress tolerance in horticultural plants through melatonin-mediated phytohormonal crosstalk.Plant cell reports · 2024Review
126 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melatonin (N-acetyl-5-methoxytryptamine), a well-known animal hormone, is also involved in plant development and abiotic stress responses. In this study, it is shown that exogenous application of melatonin conferred improved salt, drought, and cold stress resistances in bermudagrass. Moreover, exogenous melatonin treatment alleviated reactive oxygen species (ROS) burst and cell damage induced by abiotic stress; this involved activation of several antioxidants. Additionally, melatonin-pre-treated plants exhibited higher concentrations of 54 metabolites, including amino acids, organic acids, sugars, and sugar alcohols, than non-treated plants under abiotic stress conditions. Genome-wide transcriptomic profiling identified 3933 transcripts (2361 up-regulated and 1572 down-regulated) that were differentially expressed in melatonin-treated plants versus controls. Pathway and gene ontology (GO) term enrichment analyses revealed that genes involved in nitrogen metabolism, major carbohydrate metabolism, tricarboxylic acid (TCA)/org transformation, transport, hormone metabolism, metal handling, redox, and secondary metabolism were over-represented after melatonin pre-treatment. Taken together, this study provides the first evidence of the protective roles of exogenous melatonin in the bermudagrass response to abiotic stresses, partially via activation of antioxidants and modulation of metabolic homeostasis. Notably, metabolic and transcriptomic analyses showed that the underlying mechanisms of melatonin could involve major reorientation of photorespiratory and carbohydrate and nitrogen metabolism.
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