ArticlePaediatric and perinatal epidemiology2014
Body size and risk of spontaneous abortion among danish pregnancy planners.
Article in Paediatric and perinatal epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Progestogen therapy in threatened miscarriage and unexplained recurrent pregnancy loss: Recommendations by the Thai interest group.The journal of obstetrics and gynaecology research · 2025Guideline
- Association between maternal adiposity measures and infant health outcomes: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Pooled it
- Progestogen for treating threatened miscarriage.The Cochrane database of systematic reviews · 2018Pooled it
- The relevance of female overweight in infertility treatment: a position statement of the Italian Society of Fertility and Sterility and Reproductive Medicine (SIFES-MR).Journal of assisted reproduction and genetics · 2025Article
- Preconception and Early-Pregnancy Body Mass Index in Women and Men, Time to Pregnancy, and Risk of Miscarriage.JAMA network open · 2024Article
- Predictive models of miscarriage on the basis of data from a preconception cohort study.Fertility and sterility · 2024Article
- Article
- Associations between obesity, smoking behaviors, reproductive traits and spontaneous abortion: a univariable and multivariable Mendelian randomization study.Frontiers in endocrinology · 2023Article
- Adherence to Nordic dietary patterns and risk of first-trimester spontaneous abortion.European journal of nutrition · 2022Article
- Recurrent Spontaneous Miscarriage: a Comparison of International Guidelines.Geburtshilfe und Frauenheilkunde · 2021Article
- The threshold effect of factors associated with spontaneous abortion in human-assisted reproductive technology.Scientific reports · 2021Article
- Review
- The Prevalence and Impact of Polycystic Ovary Syndrome in Recurrent Miscarriage: A Retrospective Cohort Study and Meta-Analysis.Journal of clinical medicine · 2020Article
- Factors associated with spontaneous abortion following intracytoplasmic sperm injection (ICSI).JBRA assisted reproduction · 2019Article
- Waist circumference in relation to outcomes of infertility treatment with assisted reproductive technologies.American journal of obstetrics and gynecology · 2019 · on this mapArticle
- Pregnancy loss and risk of later dementia: A nationwide cohort study, Denmark, 1977-2017.Alzheimer's & dementia (New York, N. Y.) · 2019Article
- Recurrent Miscarriage: Diagnostic and Therapeutic Procedures. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry Number 015/050).Geburtshilfe und Frauenheilkunde · 2018Article
- Extremities of body mass index and their association with pregnancy outcomes in women undergoing in vitro fertilization in the United States.Fertility and sterility · 2016Article
- Lifestyle and pregnancy loss in a contemporary cohort of women recruited before conception: The LIFE Study.Fertility and sterility · 2016Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundSeveral studies indicate that female obesity increases the risk of spontaneous abortion (SAB). Central adiposity, height, and location of typical weight gain have not been examined as risk factors for SAB.
methodsWe examined the associations between selected anthropometric factors and risk of SAB among 5132 women enrolled in a Danish Internet-based prospective cohort study of pregnancy planners. We used Cox proportional hazards regression models, with gestational weeks as the time scale, to compute hazard ratios (HRs) of SAB and 95% confidence intervals (CIs).
resultsAfter adjustment for potential confounders, the HRs for SAB among underweight (body mass index (BMI, kg/m(2) ) <20), overweight (BMI: 25-29) and obese (BMI ≥30) women were 1.00 [95% CI: 0.81, 1.24], 0.90 [95% CI: 0.73, 1.09] and 1.23 [95% CI: 0.98, 1.54], respectively, compared with normal weight women (BMI 20-24). The association between obesity and SAB was stronger for early SAB (<8 weeks gestation); HR: 1.34 95% CI: 1.01, 1.77. The HR for height ≥174 cm vs. <166 cm was 0.81 [95% CI: 0.66, 1.00]. Increased waist-to-hip ratio (WHR) was inversely associated with risk of SAB (HR: 0.81; 95% CI: 0.63, 1.05). Waist circumference and location of typical weight gain were not appreciably associated with SAB risk.
conclusionsThis study confirms previous studies that have shown a small positive association between obesity and SAB risk. Our results suggest that obesity is a stronger risk factor for early pregnancy losses, and that small stature and low WHR are associated with an increased risk of SAB.
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