Trial reportPaediatric and perinatal epidemiology2014
Impact of instruction in the Creighton model fertilitycare system on time to pregnancy in couples of proven fecundity: results of a randomised trial.
Trial report in Paediatric and perinatal epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00161395 (Randomized Trial of Fertility Awareness and Time to Pregnancy in Couples of Normal Fertility), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Trial of Fertility Awareness and Time to Pregnancy in Couples of Normal Fertility
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Timed intercourse for couples trying to conceive.The Cochrane database of systematic reviews · 2023Pooled it
- A randomized trial of web-based fertility-tracking software and fecundability.Fertility and sterility · 2023Trial
- Comparison of woman-picked, expert-picked, and computer-picked Peak Day of cervical mucus with blinded urine luteinising hormone surge for concurrent identification of ovulation.Paediatric and perinatal epidemiology · 2020Trial
- Review
- Translation and Cultural Adaptation of the Creighton Model FertilityCare™ System Follow-up Form to Brazilian Portuguese.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Article
- The association between the use of fertility indicators and fecundability in a Danish preconception cohort.Paediatric and perinatal epidemiology · 2024Article
- Usefulness of the Sympto-Thermal Method with Standardized Cervical Mucus Assessment (InVivo Method) for Evaluating the Monthly Cycle in Women with Polycystic Ovary Syndrome (PCOS).Healthcare (Basel, Switzerland) · 2024Article
- Large-Scale Data Harmonization Across Prospective Studies.American journal of epidemiology · 2023Article
- Does a short luteal phase correlate with an increased risk of miscarriage? A cohort study.BMC pregnancy and childbirth · 2022Article
- Feasibility of leveraging menstrual cycle tracking apps for preconception research recruitment.Frontiers in reproductive health · 2022Article
- Fertility Awareness-Based Methods for Women's Health and Family Planning.Frontiers in medicine · 2022Review
- Characteristics of menstrual cycles with or without intercourse in women with no known subfertility.Human reproduction open · 2022Article
- Cervical mucus patterns and the fertile window in women without known subfertility: a pooled analysis of three cohorts.Human reproduction (Oxford, England) · 2021Article
- Predictive Factors of Conception and the Cumulative Pregnancy Rate in Subfertile Couples Undergoing Timed Intercourse With Ultrasound.Frontiers in endocrinology · 2021Article
- Fecundability in relation to use of mobile computing apps to track the menstrual cycle.Human reproduction (Oxford, England) · 2020Observational
- Menstrual bleeding, cycle length, and follicular and luteal phase lengths in women without known subfertility: A pooled analysis of three cohorts.Paediatric and perinatal epidemiology · 2020Article
- Daily perceived stress and time to pregnancy: A prospective cohort study of women trying to conceive.Psychoneuroendocrinology · 2019Article
- The Preconception Period analysis of Risks and Exposures Influencing health and Development (PrePARED) consortium.Paediatric and perinatal epidemiology · 2019Article
- Fecundability in relation to use of fertility awareness indicators in a North American preconception cohort study.Fertility and sterility · 2019Article
- Compliance with daily, home-based collection of urinary biospecimens in a prospective, preconception cohort.Environmental epidemiology (Philadelphia, Pa.) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe Creighton Model FertilityCare System (CrMS) teaches women to identify days when intercourse is likely to result in pregnancy. We sought to assess the impact of the CrMS on time to pregnancy (TTP), via per-cycle pregnancy rates (fecundability).
methodsWe conducted a parallel randomised trial at the University of Utah School of Medicine, 2003-06. Women ages 18-35 years, in a relationship of proven fertility, who desired to conceive, were block-randomised and stratified for age, with allocation concealment by opaque sequentially numbered sealed envelopes. The control group received the advice to have intercourse 2-3 times per week, and the intervention group received CrMS instruction. All women were asked to begin trying to conceive starting the second cycle in the study and were followed actively up to seven cycles, without blinding of research personnel. We calculated descriptive statistics and fecundability, and estimated Cox models for TTP. (Clinicaltrials.gov NCT00161395).
resultsThere were 143 women randomised: 71 to the control group (all analysed) and 72 to the CrMS group (69 analysed). The adjusted hazard ratio for the influence of CrMS on TTP was 0.86 [95% confidence interval (CI): 0.53, 1.38]. Fecundability in cycles with intent to conceive was 31% in controls and 36% with CrMS (P = 0.32). By the first cycle, fecundability was 17% in controls, and 4% with CrMS (P = 0.02). No adverse events were reported.
conclusionsWe found no significant impact of CrMS on TTP or fecundability, but fewer of the women receiving CrMS conceived by the first cycle.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.