ArticleThe Kaohsiung journal of medical sciences2014
Isolation, screening and partial purification of antimicrobial antibiotics from soil Streptomyces sp. SCA 7.
Article in The Kaohsiung journal of medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
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- Unveiling the Diversity of Culturable Microbes from the Underexplored Mingyong Glacier Landscape: A Roadmap for Leveraging the Potential of Actinomycetota.Indian journal of microbiology · 2025Article
- Degradation of polyvinyl chloride (PVC) microplastics employing the actinobacterial strain Streptomyces gobitricini.Biodegradation · 2025Article
- Identification, Characterization, and Production Optimization of 6-Methoxy-1H-Indole-2-Carboxylic Acid Antifungal Metabolite Produced byMicroorganisms · 2023Article
- Anti-Microorganisms · 2023Review
- Enhancing the Antibiotic Production by Thermophilic Bacteria Isolated from Hot Spring Waters via Ethyl Methanesulfonate Mutagenesis.Antibiotics (Basel, Switzerland) · 2023Article
- Dietary Frankincense (Animals : an open access journal from MDPI · 2023Article
- Diversity and Biotechnological Potential of Marine Actinomycetes from India.Indian journal of microbiology · 2022Review
- Overview on Strategies and Assays for Antibiotic Discovery.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Phylogenetic affiliation of endophytic actinobacteria associated with selected orchid species and their role in growth promotion and suppression of phytopathogens.Frontiers in plant science · 2022Article
- Secretion of poly-γ-glutamic acid byFrontiers in microbiology · 2022Article
- Article
- Post-translational regulation of autophagy is involved in intra-microbiome suppression of fungal pathogens.Microbiome · 2021Article
- The profile of the soil microbiota in the Cerrado is influenced by land use.Applied microbiology and biotechnology · 2021Article
- Antagonistic Potential of SoilInternational journal of microbiology · 2021Article
- An overview on natural farnesyltransferase inhibitors for efficient cancer therapy.Journal of enzyme inhibition and medicinal chemistry · 2020Review
- Potentials of Actinomycetes from Reserved Environments as Antibacterial Agents Against Drug-Resistant Clinical Bacterial Strains.Ethiopian journal of health sciences · 2020Article
- A Newly IsolatedFrontiers in microbiology · 2020Article
- Streptomyces sp. MUM273b: A mangrove-derived potential source for antioxidant and UVB radiation protectants.MicrobiologyOpen · 2019Article
- Mangrove derived Streptomyces sp. MUM265 as a potential source of antioxidant and anticolon-cancer agents.BMC microbiology · 2019Article
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3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thirty-seven actinomycetes strains were isolated from soil samples collected from an agriculture field in Vengodu, Thiruvannamalai District, Tamil Nadu, India (latitude: 12° 54' 0033″, North; longitude: 79° 78' 5216″, East; elevation: 228.6/70.0 ft/m). The isolates were assessed for antagonistic activity against five Gram-positive bacteria, seven Gram-negative bacteria, and two pathogenic fungi. During the initial screening, 43% of the strains showed weak activity, 16% showed moderate activity, 5% showed good activity, and 35% showed no antagonistic activity. Among the strains tested, SCA 7 showed strong antimicrobial activity. Maximum biological activity was obtained on modified nutrient glucose agar (MNGA) medium. The mycelia of SCA 7 were extracted with methanol and tested against microbial pathogens using the disc diffusion method. The crude extract was purified partially using column chromatography and assessed for antimicrobial activity. Fraction 10 showed good activity against Staphylococcus epidermidis (31.25 μg/mL) and Malassezia pachydermatis (500 μg/mL) and the active principle (fraction 10) was identified as 2,4-bis (1,1-dimethylethyl) phenol. Based on morphological, physiological, biochemical, cultural, and molecular characteristics (16S rDNA sequencing), this strain was identified as Streptomyces sp. SCA 7. It could be used in the development of new substances for pharmaceutical or agricultural purposes.
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