Evidence map›Paper›PMID 25224635›Full record

ArticleReproductive biology and endocrinology : RB&E2014

The prevalence of metabolic disorders in various phenotypes of polycystic ovary syndrome: a community based study in Southwest of Iran.

Fahimeh Ramezani Tehrani, Homeira Rashidi, Mahnaz Bahri Khomami, Maryam Tohidi, Fereidoun Azizi

Abstract read
In one paragraph

Article in Reproductive biology and endocrinology : RB&E, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Targeted metabolomics and fatty acid profiling in lean and obese polycystic ovarian syndrome patients: A pilot study.European journal of obstetrics & gynecology and reproductive biology: X · 2026
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  11. Are menstrual disorders in adolescent girls related to metabolic disorders?Pediatric endocrinology, diabetes, and metabolism · 2023
    Article
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  13. Role of Oxidative Stress in Obese and Nonobese PCOS Patients.International journal of clinical practice · 2022
    Article
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  17. Review
  18. Polycystic Ovary Syndrome in Adolescents: Challenges in Diagnosis and Treatment.International journal of endocrinology and metabolism · 2019
    Review
  19. Article
  20. The glucose metabolism disorder and dyslipidemia among girls with different phenotype polycystic ovary syndrome.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fahimeh Ramezani Tehrani
Homeira RashidiDiabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. hrashidi@ajums.ac.ir.
Mahnaz Bahri Khomami
Maryam Tohidi
Fereidoun Azizi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolycystic ovary syndrome (PCOS) is a common endocrinopathy, associated with metabolic abnormalities. Metabolic features of various phenotypes of this syndrome are still debatable. The aim of present study hence was to evaluate the metabolic and hormonal features of PCOS phenotypes in comparison to a group of healthy control.

methodsA total of 646 reproductive-aged women were randomly selected using the stratified, multistage probability cluster sampling method. The subjects were divided into five phenotypes: A (oligo/anovulation + hyperandrogenism + polycystic ovaries), B (oligo/anovulation + hyperandrogenism), C (hyperandrogenism + polycystic ovaries) and D (oligo/anovulation + polycystic ovaries). Hormonal and metabolic profiles and the prevalence of metabolic syndrome among these groups were compared using ANCOVA adjusted for age and body mass index.

resultsAmong women with PCOS (n = 85), those of groups A and C had higher serum levels of insulin and homeostatic model assessment for insulin resistance (HOMA-IR), compared to PCOS women of group D. Serum concentrations of cholesterol, low density lipoprotein, triglycerides and glucose in group A were higher than in other phenotypes, whereas the metabolic syndrome was more prevalent among group B.

conclusionsWomen who had all three components of the syndrome showed the highest level of metabolic disturbances indicating that metabolic screening of the severest phenotype of PCOS may be necessary.

Indexed as

Insulin ResistanceAdultAnovulationCluster AnalysisFemaleHumansHyperandrogenismIranMetabolic SyndromeOvaryPolycystic Ovary SyndromePrevalenceSeverity of Illness IndexUltrasonographyYoung Adult

Identifiers

PMID25224635
PMCPMC4180586

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.