ArticleAntimicrobial agents and chemotherapy2014
New insights into the in vitro susceptibility of Pythium insidiosum.
Article in Antimicrobial agents and chemotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 54 citations in OpenAlex.
- In Vitro Screening of Microbial Extracts Against the OomycetesBio-protocol · 2025Article
- Next-generation antifungal drugs: Mechanisms, efficacy, and clinical prospects.Acta pharmaceutica Sinica. B · 2025Review
- Pythium insidiosum-antigen enhances neutrophil-mediated killing of zoospores.Scientific reports · 2025Article
- Worldwide distribution of human pythosis and biological characteristics of aFrontiers in medicine · 2025Article
- ThePeerJ · 2025Review
- Treating Pythiosis with Antibacterial Drugs Targeting Protein Synthesis: An Overview.Journal of fungi (Basel, Switzerland) · 2024Review
- In vitro and ex vivo anti-Pythium insidiosum potential of ozonated sunflower oil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Strategies of Pharmacological Repositioning for the Treatment of Medically Relevant Mycoses.Infection and drug resistance · 2024Review
- Selection of an Appropriate In Vitro Susceptibility Test for Assessing Anti-Journal of fungi (Basel, Switzerland) · 2022Article
- Pythium insidiosum Keratitis: Past, Present, and Future.Ophthalmology and therapy · 2022Review
- A Review: Antimicrobial Therapy for Human Pythiosis.Antibiotics (Basel, Switzerland) · 2022Review
- Severe skin and subcutaneous pythiosis in China: Metagenomic identification and characterization ofFrontiers in microbiology · 2022Article
- History and Perspective of Immunotherapy for Pythiosis.Vaccines · 2021Review
- Drug repurposing strategies in the development of potential antifungal agents.Applied microbiology and biotechnology · 2021Review
- Article
- Retrospective multifactorial analysis ofIndian journal of ophthalmology · 2021Review
- Human Pythiosis: Emergence of Fungal-Like Organism.Mycopathologia · 2020Review
- Successful management of cutaneous paralagenidiosis in a dog treated with mefenoxam, minocycline, prednisone, and hyperbaric oxygen therapy.Medical mycology case reports · 2020Article
- Severe meningoencephalitis secondary to calvarial invasion ofOpen veterinary journal · 2020Article
- Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have determined the in vitro activity of several antibacterial and antifungal drugs against Pythium insidiosum using broth microdilution (BMD), disk diffusion, and Etest methods. The largest zones of inhibition (disk diffusion) and the lowest BMD and Etest MICs were observed for azithromycin, clarithromycin, linezolid, mupirocin, doxycycline, minocycline, and tigecycline. The in vitro activities observed suggest that antibacterials, which act by inhibiting protein synthesis, are promising candidate therapies for the treatment of pythiosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.