ArticleJournal of biomedical optics2014
Microvascular quantification based on contour-scanning photoacoustic microscopy.
Article in Journal of biomedical optics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Vascular regional analysis unveils differential responses to anti-angiogenic therapy in pancreatic xenografts through macroscopic photoacoustic imaging.Theranostics · 2025Article
- Sound Out the Deep Clarity: Super-Resolution Photoacoustic Imaging at Depths.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024Review
- Resolution Enhancement Strategies in Photoacoustic Microscopy: A Comprehensive Review.Micromachines · 2024Review
- Article
- Functional photoacoustic imaging: from nano- and micro- to macro-scale.Nano convergence · 2023Review
- Deep Learning-Powered Bessel-Beam Multiparametric Photoacoustic Microscopy.IEEE transactions on medical imaging · 2022Article
- The Optical Coherence Tomography and Raman Spectroscopy for Sensing of the Bone Demineralization Process.Sensors (Basel, Switzerland) · 2021Article
- Integrating photoacoustic microscopy with other imaging technologies for multimodal imaging.Experimental biology and medicine (Maywood, N.J.) · 2021Review
- In vivo volumetric monitoring of revascularization of traumatized skin using extended depth-of-field photoacoustic microscopy.Frontiers of optoelectronics · 2020Article
- Side-viewing photoacoustic waveguide endoscopy.Photoacoustics · 2020Article
- Review on practical photoacoustic microscopy.Photoacoustics · 2019Review
- Optical coherence tomography-guided dynamic focusing for combined optical and mechanical scanning multimodal photoacoustic microscopy.Journal of biomedical optics · 2019Article
- Cortex-wide multiparametric photoacoustic microscopy based on real-time contour scanning.Neurophotonics · 2019Article
- Integrated multimodal photoacoustic microscopy with OCT- guided dynamic focusing.Biomedical optics express · 2019Article
- Synthetic Bessel light needle for extended depth-of-field microscopy.Applied physics letters · 2018Article
- Ultrasound-aided Multi-parametric Photoacoustic Microscopy of the Mouse Brain.Scientific reports · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Accurate quantification of microvasculature remains of interest in fundamental pathophysiological studies and clinical trials. Current photoacoustic microscopy can noninvasively quantify properties of the microvasculature, including vessel density and diameter, with a high spatial resolution. However, the depth range of focus (i.e., focal zone) of optical-resolution photoacoustic microscopy (OR-PAM) is often insufficient to encompass the depth variations of features of interest—such as blood vessels—due to uneven tissue surfaces. Thus, time-consuming image acquisitions at multiple different focal planes are required to maintain the region of interest in the focal zone. We have developed continuous three-dimensional motorized contour-scanning OR-PAM, which enables real-time adjustment of the focal plane to track the vessels’ profile. We have experimentally demonstrated that contour scanning improves the signal-to-noise ratio of conventional OR-PAM by as much as 41% and shortens the image acquisition time by 3.2 times. Moreover, contour-scanning OR-PAM more accurately quantifies vessel density and diameter, and has been applied to studying tumors with uneven surfaces.
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Registered trials
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