The NeuroPace trial: missing knowledge and insights.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Deep brain and cortical stimulation for epilepsy.The Cochrane database of systematic reviews · 2017
   Pooled it
2. Stabilizing fractional dynamical networks suppresses epileptic seizures.Scientific reports · 2026
   Article
3. Modulating limbic circuits in temporal lobe epilepsy: impacts on seizures, memory, mood and sleep.Brain communications · 2025
   Article
4. Case report: Bridging limbic network epilepsy with psychiatric, memory, and sleep comorbidities: case illustrations of reversible psychosis symptoms during continuous, high-frequency ANT-DBS.Frontiers in network physiology · 2024
   Article
5. Distributed brain co-processor for tracking spikes, seizures and behaviour during electrical brain stimulation.Brain communications · 2022
   Article
6. Financial Conflicts of Interest of United States-Based Authors in Neurology Journals: Cross-Sectional Study Using the Open Payments Database.Neurology · 2021
   Article
7. Integrating Brain Implants With Local and Distributed Computing Devices: A Next Generation Epilepsy Management System.IEEE journal of translational engineering in health and medicine · 2018
   Article
8. A Comparison of Machine Learning Classifiers for Energy-Efficient Implementation of Seizure Detection.Frontiers in systems neuroscience · 2018
   Article
9. Critical review of the responsive neurostimulator system for epilepsy.Medical devices (Auckland, N.Z.) · 2015
   Review

Corrections and comments

• Commented on by
  In response: The RNS System multicenter randomized double-blinded controlled trial of responsive cortical stimulation for adjunctive treatment of intractable partial epilepsy: knowledge and insights gained.2014
• Comment on
  Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: final results of the RNS System Pivotal trial.2014
• Erratum issued
  Corrigendum.2019

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as