Evidence map›Paper›PMID 25222799›Full record

Trial reportJournal of consulting and clinical psychology2015

Parental psychopathology and treatment outcome for anxious youth: roles of family functioning and caregiver strain.

Jessica L Schleider, Golda S Ginsburg, Courtney P Keeton, John R Weisz, Boris Birmaher, Phillip C Kendall, John Piacentini, Joel Sherrill, John T Walkup

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 65 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Family-Based Treatment for Anxiety, Depression, and ADHD for a Parent and Child.International journal of environmental research and public health · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Parenting Stress Among Caregivers of Children With Bipolar Spectrum Disorders.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2018
    Article
  17. Treatment Concerns and Functional Impairment in Pediatric Anxiety.Child psychiatry and human development · 2016
    Article
  18. Monotherapy Insufficient in Severe Anxiety? Predictors and Moderators in the Child/Adolescent Anxiety Multimodal Study.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Article
  19. Article
  20. Moderators of Outcome for Youth Anxiety Treatments: Current Findings and Future Directions.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Jessica L SchleiderDepartment of Psychology.
Golda S GinsburgPsychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine.
Courtney P KeetonPsychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine.
John R WeiszDepartment of Psychology.
Boris BirmaherDepartment of Psychiatry, University of Pittsburgh.
Phillip C KendallDepartment of Psychology, Temple University.
John PiacentiniDivision of Child and Adolescent Psychiatry, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles.
Joel SherrillDivision of Services and Intervention Research, National Institute of Mental Health.
John T WalkupDepartment of Psychiatry, Weill Cornell Medical College.
Johns Hopkins University · USAmerican Academy of Child and Adolescent Psychiatry · USCornell University · USNational Institute of Mental Health · CZTemple University · USUniversity of Pittsburgh · US

Funding

Child/Adolescent Anxiety Multimodal Treatment StudyU01MH064089 · NIMH · JOHNS HOPKINS UNIVERSITY · PI GINSBURG, GOLDA SUSAN · 2002 to 2007
$3.1M
Child/Adolescent Anxiety Multimodal Treatment StudyU01MH064003 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRMAHER, BORIS · 2002 to 2007
$2.7M
Child/Adolescent Anxiety Multimodal Treatment Study (CAMS)U01MH064092 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ALBANO, ANNE MARIE · 2002 to 2007
$2.4M
Child and Adolescent Anxiety Multisite Study (CAMS)U01MH064107 · NIMH · DUKE UNIVERSITY · PI MARCH, JOHN S · 2002 to 2007
$2.4M
Child/Adolescent Anxiety Multimodal Treatment StudyU01MH063747 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI KENDALL, PHILIP C · 2002 to 2007
$2.2M
Child/Adolescent Anxiety Multimodal Treatment StudyU01MH064088 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PIACENTINI, JOHN C. · 2002 to 2007
$2.1M
5/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH064107 · NIMH · DUKE UNIVERSITY · PI COMPTON, SCOTT N · 2010 to 2014
$1.3M
3/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH064089 · NIMH · JOHNS HOPKINS UNIVERSITY · PI GINSBURG, GOLDA SUSAN, KEETON, COURTNEY PIERCE · 2010 to 2014
$925k
2/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH064003 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SAKOLSKY, DARA JENNIFER · 2010 to 2014
$659k
Integrating Biological Markers into Clinical ResearchK24MH096760 · NIMH · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI GINSBURG, GOLDA SUSAN · 2013 to 2016
$653k
4/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH063747 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI KENDALL, PHILIP C · 2010 to 2014
$618k
6/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH064088 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PIACENTINI, JOHN C. · 2010 to 2014
$611k
NIMH NIH HHS K24 MH096760NIMH NIH HHS MH064092NIMH NIH HHS MH63747NIMH NIH HHS MH64003NIMH NIH HHS MH64088NIMH NIH HHS MH64089NIMH NIH HHS MH64107NIMH NIH HHS R01 MH063747NIMH NIH HHS R01 MH064003NIMH NIH HHS R01 MH064088NIMH NIH HHS R01 MH064089NIMH NIH HHS R01 MH064092NIMH NIH HHS R01 MH064107NIMH NIH HHS U01 MH063747NIMH NIH HHS U01 MH064003NIMH NIH HHS U01 MH064088NIMH NIH HHS U01 MH064089NIMH NIH HHS U01 MH064092NIMH NIH HHS U01 MH064107
6 · The paper itself

Abstract

objectiveResearch has examined the effects of parental psychopathology, family functioning, and caregiver strain on treatment response in anxious youths. Although these variables have shown individual links to youth treatment response, theoretical models for their combined effects remain unexplored. This study tested the hypothesis that improvements in family functioning and reductions in caregiver strain explained the effects of parental psychopathology on youth treatment outcome in an anxiety treatment trial.

methodA multiple mediation technique was used to test the proposed model across independent evaluator (IE), parent, and youth informants in 488 youths, aged 7-17 years (50% female; mean age = 10.7) meeting Diagnostic and Statistical Manual of Mental Disorders criteria for social phobia, separation anxiety, and/or generalized anxiety disorder. Youths were randomized to receive 12 weeks of cognitive-behavioral treatment (Coping Cat), medication (sertraline), their combination, or a pill placebo. At pre- and posttreatment, parents completed self-report measures of global psychopathology symptoms, family functioning, and caregiver strain; parents, youths, and IEs rated youths' anxiety symptom severity.

resultsChanges in family functioning and caregiver strain jointly explained relations between parental psychopathology and reductions in youth anxiety. Specifically, across IE and parent informants, families with higher pretreatment parental psychopathology showed more improvement in family functioning and caregiver strain, which in turn predicted greater youth anxiety reductions. Further, higher pretreatment parental psychopathology predicted greater caregiver strain reductions and, in turn, greater youth anxiety reductions, based on youths' reports of their own anxiety.

conclusionsFindings suggest that improvements in family functioning and reductions in caregiver strain can influence treatment outcomes for anxious youths, especially among youths with more distressed parents.

Indexed as

AdolescentAnimalsAntidepressive AgentsAnxiety DisordersCaregiversChildChild of Impaired ParentsCognitive Behavioral TherapyFamilyFemaleHumansMaleMental DisordersParentsSelf ReportSertralineAntidepressive AgentsSertraline

Identifiers

PMID25222799
PMCPMC4324058
OpenAlexW2332964059

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.