Observational studyThe Indian journal of medical research2014
Level of suboptimal adherence to first line antiretroviral treatment & its determinants among HIV positive people in India.
Observational study in The Indian journal of medical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Associations Between Anxiety and Adherence to Antiretroviral Medications in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis.AIDS and behavior · 2019Pooled it
- Residential mobility and health among people with HIV: a scoping review.AIDS (London, England) · 2026Article
- The prevalence of anxiety disorders among people living with HIV in India: A systematic review and meta-analysis.Indian journal of psychiatry · 2026Review
- Multilevel Syndemic Profiles Impacting Optimal ART Adherence among Trans Women Living with HIV in Mumbai and New Delhi, India: A Latent Class Analysis.International journal of transgender health · 2025Article
- Cost-effectiveness analysis of 'test and treat' policy for antiretroviral therapy among heterosexual HIV population in India.The Indian journal of medical research · 2022Article
- Two strains and drug adherence: An HIV model in the paradigm of community transmission.Nonlinear dynamics · 2022Article
- What influences adherence among HIV patients presenting with first-line antiretroviral therapy failure (ART failure)? A retrospective, cross-sectional study from a private clinic in Nagpur, India.Journal of family medicine and primary care · 2020Article
- The burden of anxiety among people living with HIV during the COVID-19 pandemic in Pune, India.BMC public health · 2020Article
- A Behavioral Adherence Intervention Improves Rates of Viral Suppression Among Adherence-Challenged People Living with HIV in South India.AIDS and behavior · 2020Article
- Level of Medication Adherence and Its Associated Factors among Patients Receiving Antiretroviral Therapy at a Tertiary Care Hospital in South India.Journal of caring sciences · 2020Article
- Determinants contributing for poor adherence to antiretroviral therapy: A hospital record-based study in Balasore, Odisha.Journal of family medicine and primary care · 2019Article
- Determination of medication adherence and related factors among people living with HIV/AIDS in a Turkish university hospitalTurkish journal of medical sciences · 2019Article
- Relationships Among Adherence and Physical and Mental Health Among Women Living with HIV in Rural India.AIDS and behavior · 2018Article
- A Study of Compliance to Antiretroviral Therapy among HIV Infected Patients at a Tertiary Care Hospital in North Karnataka.Journal of clinical and diagnostic research : JCDR · 2016Article
- A Qualitative Study to Identify the Perceptions of Adherence to Antiretroviral Therapy among People Living with HIV.Indian journal of community medicine : official publication of Indian Association of Preventive & Social MedicineArticle
- Review
- A study of adherence to antiretroviral therapy in a tertiary care hospital at Allahabad, India.Indian journal of sexually transmitted diseases and AIDSArticle
- World Health Organization Dimensions of Adherence to Antiretroviral Therapy: A Study at Antiretroviral Therapy Centre, Aligarh.Indian journal of community medicine : official publication of Indian Association of Preventive & Social MedicineArticle
- Anti-retroviral therapy adherence in India (2012-18): A systematic review and meta-analysis.Indian journal of sexually transmitted diseases and AIDSArticle
- A cross-sectional study of the factors influencing adherence to antiretroviral therapy among adults with human immunodeficiency virus infection in a tertiary care hospital in Puducherry, India.Indian journal of sexually transmitted diseases and AIDSArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
objectivesNational Anti-retroviral treatment (ART) programme in India was launched in 2004. Since then, there has been no published country representative estimate of suboptimal adherence among people living with HIV (PLHIV) on first line ART in public settings. Hence a multicentric study was undertaken in 15 States of India to assess the level of suboptimal adherence and its determinants among PLHIV.
methodsUsing a prospective observational study design, 3285 PLHIV were enrolled and followed up to six months across 30 ART centres in India. Adherence was assessed using pill count and self-reported recall method and determinants of suboptimal adherence were explored based on the responses to various issues as perceived by them.
resultsSuboptimal adherence was found in 24.5 per cent PLHIV. Determinants of suboptimal adherence were illiteracy (OR--1.341, CI--1.080-1.665), on ART for less than 6 months (OR--1.540, CI--1.280-1.853), male gender (OR for females--0.807, CI--0.662-0.982), tribals (OR--2.246, CI--1.134-4.447), on efavirenz (EFA) regimen (OR--1.479, CI--1.190-1.837), presence of anxiety (OR--1.375, CI--1.117-1.692), non-disclosure of HIV status to family (OR--1.549, CI--1.176-2.039), not motivated for treatment (OR--1.389, CI--1.093-1.756), neglect from friends (OR--1.368, CI--1.069-1.751), frequent change of residence (OR--3.373, CI--2.659-4.278), travel expenses (OR--1.364, CI--1.138-1.649), not meeting the PLHIV volunteer/community care coordinator at the ART center (OR--1.639, CI--1.330-2.019). INTERPRETATION &
conclusionsTo enhance identification of PLHIV vulnerable to suboptimal adherence, the existing checklist to identify the barriers to adherence in the National ART Guidelines needs to be updated based on the study findings. Quality of comprehensive adherence support services needs to be improved coupled with vigilant monitoring of adherence measurement.
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