ReviewMarine drugs2014
Mugilid fish are sentinels of exposure to endocrine disrupting compounds in coastal and estuarine environments.
Review in Marine drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 43 citations in OpenAlex.
- Article
- Review
- Polycyclic Aromatic Hydrocarbons in Marine Environments Affect Fish Reproduction-A Critical Review.Toxics · 2025Review
- Synchronously Mature Intersex Japanese Flounder (Animals : an open access journal from MDPI · 2024Article
- Method for the molecular and quantitative identification of oocytes and their developmental stage in teleost fish gonads.MethodsX · 2024Article
- Article
- Non-coding RNA Expression Patterns of Two Different Teleost Gonad Maturation Stages.Marine biotechnology (New York, N.Y.) · 2020Article
- Article
- Endocrine-disrupting chemicals in aquatic environment: what are the risks for fish gametes?Fish physiology and biochemistry · 2018Review
- Assessment of the Health Status of MusselsFrontiers in physiology · 2018Article
- The Increasing Prevalence in Intersex Variation from Toxicological Dysregulation in Fetal Reproductive Tissue Differentiation and Development by Endocrine-Disrupting Chemicals.Environmental health insights · 2016Review
- Article
- Gonadal disorder in the thinlip grey mullet (Liza ramada, Risso 1827) as a biomarker of environmental stress in surface waters.International journal of environmental research and public health · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effects on fish reproduction can result from a variety of toxicity mechanisms first operating at the molecular level. Notably, the presence in the environment of some compounds termed endocrine disrupting chemicals (EDCs) can cause adverse effects on reproduction by interfering with the endocrine system. In some cases, exposure to EDCs leads to the animal feminization and male fish may develop oocytes in testis (intersex condition). Mugilid fish are well suited sentinel organisms to study the effects of reproductive EDCs in the monitoring of estuarine/marine environments. Up-regulation of aromatases and vitellogenins in males and juveniles and the presence of intersex individuals have been described in a wide array of mullet species worldwide. There is a need to develop new molecular markers to identify early feminization responses and intersex condition in fish populations, studying mechanisms that regulate gonad differentiation under exposure to xenoestrogens. Interestingly, an electrophoresis of gonad RNA, shows a strong expression of 5S rRNA in oocytes, indicating the potential of 5S rRNA and its regulating proteins to become useful molecular makers of oocyte presence in testis. Therefore, the use of these oocyte markers to sex and identify intersex mullets could constitute powerful molecular biomarkers to assess xenoestrogenicity in field conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.