ArticlePloS one2014
Distribution of fitness in populations of dengue viruses.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Evolution and adaptation of dengue virus in response to high-temperature passaging in mosquito cells.Virus evolution · 2025Article
- The Development of New Primer Sets for the Amplification and Sequencing of the Envelope Gene of All Dengue Virus Serotypes.Microorganisms · 2024Article
- Dengue: A Minireview.Viruses · 2020Review
- Viral immunogenicity determines epidemiological fitness in a cohort of DENV-1 infection in Brazil.PLoS neglected tropical diseases · 2018Article
- Infection rate ofProceedings. Biological sciences · 2017Article
- Molecular Characterization of Two Major Dengue Outbreaks in Costa Rica.The American journal of tropical medicine and hygiene · 2016Article
- Dengue Vaccines: A Perspective from the Point of View of Intellectual Property.International journal of environmental research and public health · 2015Article
- Nature and Extent of Genetic Diversity of Dengue Viruses Determined by 454 Pyrosequencing.PloS one · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetically diverse RNA viruses like dengue viruses (DENVs) segregate into multiple, genetically distinct, lineages that temporally arise and disappear on a regular basis. Lineage turnover may occur through multiple processes such as, stochastic or due to variations in fitness. To determine the variation of fitness, we measured the distribution of fitness within DENV populations and correlated it with lineage extinction and replacement. The fitness of most members within a population proved lower than the aggregate fitness of populations from which they were drawn, but lineage replacement events were not associated with changes in the distribution of fitness. These data provide insights into variations in fitness of DENV populations, extending our understanding of the complexity between members of individual populations.
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