ArticleACS applied materials & interfaces2014
Injectable dopamine-modified poly(ethylene glycol) nanocomposite hydrogel with enhanced adhesive property and bioactivity.
Article in ACS applied materials & interfaces, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
What it found
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Who cites it
89 citing papers in PubMed.
- Adhesive and Hemostatic Hydrogel for the Management of Postpartum Hemorrhage.ACS applied materials & interfaces · 2026Article
- Poly(vinyl alcohol) Hydrogels for Osteoarthritis: A Review of Preparation Strategies, Modification Approaches, and Challenges.Gels (Basel, Switzerland) · 2026Review
- A click-crosslinked dopamine-functionalized hydrogel for therapeutic delivery of stem cell-derived extracellular vesicles.Biomaterials science · 2026Article
- Freeze-Thaw-Synthesized PVA/Chitosan Hydrogels: Structure-Property Relationships and ANN Modeling of Swelling and Degradation Behaviors.ACS omega · 2026Article
- Injectable Dual-Crosslinked Poly(oligo(Ethylene Glycol) Methacrylate) Hydrogels Inspired by Mussel Adhesion for Cutaneous Wound Healing and Functional Tissue Regeneration.Advanced healthcare materials · 2026Article
- Smart Polymer-Derived Injectable Hydrogels: Current Status and Future Perspectives.ACS polymers Au · 2025Review
- Immunomodulatory bioadhesive technologies.Biomaterials · 2025Review
- Degradable polymer bone adhesives.Fundamental research · 2025Review
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- Injectable Biomimetic Gels for Biomedical Applications.Biomimetics (Basel, Switzerland) · 2024Review
- Article
- Injectable Nanoengineered Adhesive Hydrogel for Treating Enterocutaneous Fistulas.Acta biomaterialia · 2024Article
- Advances in the Development of Nano-Engineered Mechanically Robust Hydrogels for Minimally Invasive Treatment of Bone Defects.Gels (Basel, Switzerland) · 2023Review
- Strongly Metal-Adhesive and Self-Healing Gelatin@Polydopamine-Based Hydrogels with Long-Term Antioxidant Activity.Antioxidants (Basel, Switzerland) · 2023Article
- Effect of nanoparticle loading and magnetic field application on the thermodynamic, optical, and rheological behavior of thermoresponsive polymer solutions.Journal of vinyl & additive technology · 2023Article
- In vivo and in vitro studies of a propolis-enriched silk fibroin-gelatin composite nanofiber wound dressing.Heliyon · 2023Article
- Self-healing hybrid hydrogels with sustained bioactive components release for guided bone regeneration.Journal of nanobiotechnology · 2023Article
- Porous Scaffolds Based on Polydopamine/Chondroitin Sulfate/Polyvinyl Alcohol Composite Hydrogels.Polymers · 2023Article
- Polypyrrole fabricated Laponite RD conductive nanocomposites: influence of grafting efficiency on structural and conductive properties.Turkish journal of chemistry · 2023Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
A synthetic mimic of mussel adhesive protein, dopamine-modified four-armed poly(ethylene glycol) (PEG-D4), was combined with a synthetic nanosilicate, Laponite (Na(0.7+)(Mg5.5Li0.3Si8)O20(OH)4)(0.7-)), to form an injectable naoncomposite tissue adhesive hydrogel. Incorporation of up to 2 wt % Laponite significantly reduced the cure time while enhancing the bulk mechanical and adhesive properties of the adhesive due to strong interfacial binding between dopamine and Laponite. The addition of Laponite did not alter the degradation rate and cytocompatibility of PEG-D4 adhesive. On the basis of subcutaneous implantation in rat, PEG-D4 nanocomposite hydrogels elicited minimal inflammatory response and exhibited an enhanced level of cellular infiltration as compared to Laponite-free samples. The addition of Laponite is potentially a simple and effective method for promoting bioactivity in a bioinert, synthetic PEG-based adhesive while simultaneously enhancing its mechanical and adhesive properties.
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Registered trials
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