Observational studyRadiology2015
Transperineal in-bore 3-T MR imaging-guided prostate biopsy: a prospective clinical observational study.
Observational study in Radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 82 citations in OpenAlex.
- Comparison of analgesic techniques in MRI-guided in-bore prostate biopsy.European radiology · 2019Trial
- Transperineal 3T MRI-guided and transrectal MRI-ultrasound fusion prostate biopsies: Do lesion location and size impact diagnostic yield?Urologic oncology · 2026Article
- In-bore MRI-guided prostate biopsy: current evidence, clinical applications, and future directions.Polish journal of radiology · 2026Review
- Image-Guided Adaptive Cryotherapy for Prostate Cancer Treatment.Annals of biomedical engineering · 2025Article
- Feasibility of MRI-Guided Transperineal Implantation of Microdevices for Drug Delivery and Response Assessment in Prostate Cancer.Journal of magnetic resonance imaging : JMRI · 2025Article
- Device-Specific Calibration Methods for Optical Frequency Domain Reflectometry-Based Shape Sensing in Catheters and Surgical Needles.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025Article
- An MR-Safe Pneumatic Stepper Motor: Design, Control, and Characterization.Journal of medical devices · 2025Article
- Novel Intraprostatic Magnetic Resonance-Guided Implantation of Multidrug-Eluting Microdevice for Testing of Systemic Therapy Agents In Situ: Proof of Concept in Intermediate-Risk and High-Risk Prostate Cancer.The Journal of urology · 2025Article
- Targeted biopsy of the prostate.Abdominal radiology (New York) · 2025Review
- 3.0-T MR-guided transgluteal in-bore-targeted prostate biopsy under local anesthesia in patients without rectal access: a single-institute experience and review of literature.Abdominal radiology (New York) · 2024Review
- Prostate biopsy approach and complication rates.Oncology letters · 2023Article
- PI-RADS 3 score: A retrospective experience of clinically significant prostate cancer detection.BJUI compass · 2023Article
- Data-driven adaptive needle insertion assist for transperineal prostate interventions.Physics in medicine and biology · 2023Article
- Automatic segmentation of prostate and extracapsular structures in MRI to predict needle deflection in percutaneous prostate intervention.International journal of computer assisted radiology and surgery · 2023Article
- Use of "Diagnostic Yield" in Imaging Research Reports: Results from Articles Published in Two General Radiology Journals.Korean journal of radiology · 2022Article
- Biomechanical modelling of the pelvic system: improving the accuracy of the location of neoplasms in MRI-TRUS fusion prostate biopsy.BMC cancer · 2022Article
- Real-Time Magnetic Resonance Imaging.Journal of magnetic resonance imaging : JMRI · 2022Review
- Diagnostic Yield of Incremental Biopsy Cores and Second Lesion Sampling for In-Gantry MRI-Guided Prostate Biopsy.AJR. American journal of roentgenology · 2021Article
- In vivo evaluation of angulated needle-guide template for MRI-guided transperineal prostate biopsy.Medical physics · 2021Article
- Role of Machine Learning and Artificial Intelligence in Interventional Oncology.Current oncology reports · 2021Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeTo determine the detection rate, clinical relevance, Gleason grade, and location of prostate cancer ( PCa prostate cancer ) diagnosed with and the safety of an in-bore transperineal 3-T magnetic resonance (MR) imaging-guided prostate biopsy in a clinically heterogeneous patient population. MATERIALS AND
methodsThis prospective retrospectively analyzed study was HIPAA compliant and institutional review board approved, and informed consent was obtained. Eighty-seven men (mean age, 66.2 years ± 6.9) underwent multiparametric endorectal prostate MR imaging at 3 T and transperineal MR imaging-guided biopsy. Three subgroups of patients with at least one lesion suspicious for cancer were included: men with no prior PCa prostate cancer diagnosis, men with PCa prostate cancer who were undergoing active surveillance, and men with treated PCa prostate cancer and suspected recurrence. Exclusion criteria were prior prostatectomy and/or contraindication to 3-T MR imaging. The transperineal MR imaging-guided biopsy was performed in a 70-cm wide-bore 3-T device. Overall patient biopsy outcomes, cancer detection rates, Gleason grade, and location for each subgroup were evaluated and statistically compared by using χ(2) and one-way analysis of variance followed by Tukey honestly significant difference post hoc comparisons.
resultsNinety biopsy procedures were performed with no serious adverse events, with a mean of 3.7 targets sampled per gland. Cancer was detected in 51 (56.7%) men: 48.1% (25 of 52) with no prior PCa prostate cancer , 61.5% (eight of 13) under active surveillance, and 72.0% (18 of 25) in whom recurrence was suspected. Gleason pattern 4 or higher was diagnosed in 78.1% (25 of 32) in the no prior PCa prostate cancer and active surveillance groups. Gleason scores were not assigned in the suspected recurrence group. MR targets located in the anterior prostate had the highest cancer yield (40 of 64, 62.5%) compared with those for the other parts of the prostate (P < .001).
conclusionIn-bore 3-T transperineal MR imaging-guided biopsy, with a mean of 3.7 targets per gland, allowed detection of many clinically relevant cancers, many of which were located anteriorly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.