ArticlePersonalized medicine2014
Translating personalized medicine using new genetic technologies in clinical practice: the ethical issues.
Article in Personalized medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- The ethical aspects of human organ-on-chip models: A mapping review.Stem cell reports · 2025Review
- Maternal obesity and ancestry distance in influencing birth outcomes.International journal of obesity (2005) · 2025Observational
- The Use of Big Data in Personalized Healthcare to Reduce Inventory Waste and Optimize Patient Treatment.Journal of personalized medicine · 2024Review
- Review
- Healthcare practice strategies for integrating personalized medicine: Management of COVID-19.World journal of clinical cases · 2021Review
- Engaging pharmacogenomics in pain management and opioid selection.Pharmacogenomics · 2021Review
- Practicality of 3D Printed Personalized Medicines in Therapeutics.Frontiers in pharmacology · 2021Review
- Investigating Married Adults' Communal Coping with Genetic Health Risk and Perceived Discrimination.Communication monographs · 2018Article
- Expert Knowledge Influences Decision-Making for Couples Receiving Positive Prenatal Chromosomal Microarray Testing Results.Culture, medicine and psychiatry · 2017Article
- "Forward-Thinking" in U.S. Biobanking.Genetic testing and molecular biomarkers · 2017Article
- The nuanced negative: Meanings of a negative diagnostic result in clinical exome sequencing.Sociology of health & illness · 2016Article
- Individual DNA samples and health information sold by 23andMe.Genetics in medicine : official journal of the American College of Medical Genetics · 2016Article
- Compare and contrast: a cross-national study across UK, USA and Greek experts regarding return of incidental findings from clinical sequencing.European journal of human genetics : EJHG · 2016Article
- Evolving Roles for Physicians and Genetic Counselors in Managing Complex Genetic Disorders.Clinical and translational gastroenterology · 2015Article
- Genomic analysis in the clinic: benefits and challenges for health care professionals and patients in Brazil.Journal of community genetics · 2015Article
- Genetics and the placebo effect: the placebome.Trends in molecular medicine · 2015Review
- Consenting for molecular diagnostics.Clinical chemistry · 2015Article
- Precision Medicine in Lifestyle Medicine: The Way of the Future?American journal of lifestyle medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The integration of new genetic technologies into clinical practice holds great promise for the personalization of medical care, particularly the use of large-scale DNA sequencing for genome-wide genetic testing. However, these technologies also yield unprecedented amounts of information whose clinical implications are not fully understood, and we are still developing technical standards for measuring sequence accuracy. These technical and clinical challenges raise ethical issues that are similar to but qualitatively different from those that we are accustomed to dealing with for traditional medical genetics. The sheer amount of information afforded by genome sequencing requires rethinking of how to implement core ethical principles including, but not limited to: informed consent, privacy and data ownership and sharing, technology regulation, issues of access, particularly as new technology is integrated into clinical practice, and issues of potential stigma and impact on perceptions of disability. In this article, we will review the issues of informed consent, privacy, data ownership and technology regulation as they relate to the emerging field of personalized medicine and genomics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.