ArticleNeural regeneration research2014
Amplitude of sensory nerve action potential in early stage diabetic peripheral neuropathy: an analysis of 500 cases.
Article in Neural regeneration research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Moxibustion combinations for diabetic peripheral neuropathy: a network meta-analysis of 40 randomised trials.Frontiers in endocrinology · 2026Pooled it
- Trial
- Article
- Paeoniflorin as a candidate disease-modifying therapy for diabetic peripheral neuropathy: mechanisms, exposure challenges, and translational priorities.Frontiers in pharmacology · 2026Review
- Improving Microcirculation With Nerve Decompression: The Missing Link in Treatment of Diabetic Neuropathy and Diabetic Foot Ulcer.International wound journal · 2025Review
- A case control study of the relationship between persistent serum creatine kinase elevation and polyneuropathy.Scientific reports · 2024Article
- Article
- Association of Sensory Nerve Action Potential Amplitude and Velocity With Type 2 Diabetic Peripheral Neuropathy.Cureus · 2023Article
- Autonomic and Somatic Nerve Functions in Type 2 Diabetes Mellitus Patients: Electrophysiological Aspects.Diagnostics (Basel, Switzerland) · 2021Article
- Ad hoc hybrid synaptic junctions to detect nerve stimulation and its application to detect onset of diabetic polyneuropathy.Biosensors & bioelectronics · 2020Article
- Sensory nerve conduction study of median ulnar and radial nerves in type 2 diabetic individuals in the age group 40-80 years.Heliyon · 2020Article
- Patterns of Nerve Conduction Abnormalities in Patients with Type 2 Diabetes Mellitus According to the Clinical Phenotype Determined by the Current Perception Threshold.Diabetes & metabolism journal · 2018Article
- Normative Data for Median Nerve Conduction in Healthy Young Adults from Punjab, India.Journal of neurosciences in rural practice · 2017Article
- Diabetic Neuropathy Evaluated by a Novel Device: Sural Nerve Conduction Is Associated with Glycemic Control and Ankle-Brachial Pressure Index in Japanese Patients with Diabetes.Frontiers in endocrinology · 2017Article
- Nerve decompression and neuropathy complications in diabetes: Are attitudes discordant with evidence?Diabetic foot & ankle · 2017Review
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Early diagnosis of diabetic peripheral neuropathy is important for the successful treatment of diabetes mellitus. In the present study, we recruited 500 diabetic patients from the Fourth Affiliated Hospital of Kunming Medical University in China from June 2008 to September 2013: 221 cases showed symptoms of peripheral neuropathy (symptomatic group) and 279 cases had no symptoms of peripheral impairment (asymptomatic group). One hundred healthy control subjects were also recruited. Nerve conduction studies revealed that distal motor latency was longer, sensory nerve conduction velocity was slower, and sensory nerve action potential and amplitude of compound muscle action potential were significantly lower in the median, ulnar, posterior tibial and common peroneal nerve in the diabetic groups compared with control subjects. Moreover, the alterations were more obvious in patients with symptoms of peripheral neuropathy. Of the 500 diabetic patients, neural conduction abnormalities were detected in 358 cases (71.6%), among which impairment of the common peroneal nerve was most prominent. Sensory nerve abnormality was more obvious than motor nerve abnormality in the diabetic groups. The amplitude of sensory nerve action potential was the most sensitive measure of peripheral neuropathy. Our results reveal that varying degrees of nerve conduction changes are present in the early, asymptomatic stage of diabetic peripheral neuropathy.
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