Evidence map›Paper›PMID 25221405›Full record

ArticleAnnals of Indian Academy of Neurology2014

Neuropsychiatric profiles in patients with Alzheimer's disease and vascular dementia.

Tushar Kanti Bandyopadhyay, Atanu Biswas, Arijit Roy, Deb Sankar Guin, Goutam Gangopadhyay, Sujit Sarkhel, Malay Kumar Ghoshal, Asit Kumar Senapati

Open access · diamondAbstract read
In one paragraph

Article in Annals of Indian Academy of Neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Depression and anxiety in vascular dementia: an update.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Neuropsychiatric symptoms among young stroke survivors-frequency, patterns, and associated factors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
  7. Article
  8. Article
  9. Behavior in subcortical vascular dementia with sight pathologies: visual hallucinations as a consequence of precocious gait imbalance and institutionalization.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
  10. Article
  11. Stroke Risk and Vascular Dementia in South Asians.Current atherosclerosis reports · 2018
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tushar Kanti BandyopadhyayDepartment of Neurology, Bangur Institute of Neurosciences, Kolkata, West Bengal, India.
Atanu BiswasDepartment of Neurology, Bangur Institute of Neurosciences, Kolkata, West Bengal, India.
Arijit RoyDepartment of Neurology, Bangur Institute of Neurosciences, Kolkata, West Bengal, India.
Deb Sankar GuinDepartment of Neurology, Bangur Institute of Neurosciences, Kolkata, West Bengal, India.
Goutam GangopadhyayDepartment of Neurology, Bangur Institute of Neurosciences, Kolkata, West Bengal, India.
Sujit SarkhelInstitute of Psychiatry, IPGME&R, Kolkata, West Bengal, India.
Malay Kumar GhoshalDepartment of Psychiatry, Calcutta Medical College, Kolkata, West Bengal, India.
Asit Kumar SenapatiDepartment of Neurology, Bangur Institute of Neurosciences, Kolkata, West Bengal, India.
Bangur Institute of Neurosciences · INInstitute of Neurosciences Kolkata · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe aim of the following study is to compare the behavioral and psychological symptoms of dementia (BPSD) in patients of Alzheimer disease (AD) and vascular dementia (VaD). MATERIALS AND

methodsWe used National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association criteria for diagnosing AD and National Institute of Neurological Disorders and Stroke-Association International pour la Recherche et l'Enseignement en Neurosciences Criteria for diagnosing VaD. VaD cohort was further subcategorized into small vessel and large vessel disease. The severity of cognitive impairment and the BPSD were studied by means of the Clinical Dementia Rating Scale (CDR) and the Neuropsychiatric Inventory respectively.

resultsWe studied 50 AD and 50 VaD patients of whom 38 were small vessels and 12 were large vessels VaD. The severity of dementia was comparable in both groups. The agitation/aggression, depression/dysphoria, anxiety, apathy/indifference, irritability, aberrant motor behavior, appetite and eating behavior and night-time behaviors occurred significantly more frequently in patients with VaD than AD. We found a weak positive correlation between the CDR score and the number of neuropsychiatric symptoms per patient in both cohorts. Elation/euphoria, agitation/aggression was significantly more frequent in patients with large vessel in comparison to small vessel VaD.

conclusionsBPSD are common in both types of dementia and they are more severe in VaD than AD when the groups have similar levels of cognitive impairment.

Indexed as

Alzheimer diseasebehavioral and psychological symptoms of dementianeuropsychiatric inventorysmall vessel diseasevascular dementia

Identifiers

PMID25221405
PMCPMC4162022
OpenAlexW2032490503

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.