Evidence map›Paper›PMID 25220652›Full record

ReviewExpert review of clinical immunology2014

Lung transplant immunosuppression - time for a new approach?

Chad A Witt, Varun Puri, Andrew E Gelman, Alexander Sasha Krupnick, Daniel Kreisel

Open access · greenAbstract readEditorialReview
In one paragraph

Review in Expert review of clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Ischemia reperfusion injury facilitates lung allograft acceptance through IL-33-mediated activation of donor-derived IL-5 producing group 2 innate lymphoid cells.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chad A WittDepartment of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Varun Puri
Andrew E Gelman
Alexander Sasha Krupnick
Daniel Kreisel
Washington University in St. Louis · US

Funding

MECHANISMS OF LUNG ALLOGRAFT ACCEPTANCER01HL113931 · NHLBI · WASHINGTON UNIVERSITY · PI KREISEL, DANIEL, KRUPNICK, ALEXANDER S. · 2012 to 2015
$1.5M
NHLBI NIH HHS R01 HL113931
6 · The paper itself

Abstract

Outcomes after lung transplantation remain worse compared to other solid organ transplants, which is in large part due to high rates of graft rejection. Despite emerging data that immune responses to lungs differ from other organs, immunosuppression for lung transplant recipients is still based on strategies established for recipients of other grafts. There exists an urgent need to develop immunosuppressive strategies for lung transplant recipients that take the unique immunological features of this organ into account.

Indexed as

Lung TransplantationHumansImmunosuppression TherapyLungPortraits as Topicadaptive immunitychronic rejectiongraft rejectionimmunosuppressioninnate immunitylung transplantation

Identifiers

PMID25220652
PMCPMC4412736
OpenAlexW2033093608

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.