Evidence map›Paper›PMID 25220619›Full record

ArticleInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2014

Molecular surveillance of rotavirus strains circulating in Yaoundé, Cameroon, September 2007-December 2012.

Angeline Boula, Diane Waku-Kouomou, Mina Njiki Kinkela, Mathew D Esona, Grace Kemajou, David Mekontso, Mapaseka Seheri, Valantine Ngum Ndze, Irene Emah, Serge Ela and 7 more

Open access · greenAbstract readHistorical Article
In one paragraph

Article in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  13. Whole genome detection of rotavirus mixed infections in human, porcine and bovine samples co-infected with various rotavirus strains collected from sub-Saharan Africa.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2015
    Article
  14. Special issue on 'genetic diversity and evolution of rotavirus strains: possible impact of global immunization programs'.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Angeline BoulaMother and Child Center, Chantal Biya Foundation, Yaoundé, Cameroon.
Diane Waku-KouomouDivision of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States. Electronic address: irf6@cdc.gov.
Mina Njiki KinkelaMother and Child Center, Chantal Biya Foundation, Yaoundé, Cameroon.
Mathew D EsonaDivision of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States.
Grace KemajouMother and Child Center, Chantal Biya Foundation, Yaoundé, Cameroon.
David MekontsoWorld Health Organization Country Office of Cameroon, Yaoundé, Cameroon.
Mapaseka SeheriMedical Research Council/Diarrhoeal Pathogens Research Unit, University of Limpopo, Medunsa Campus, South Africa.
Valantine Ngum NdzeMother and Child Center, Chantal Biya Foundation, Yaoundé, Cameroon.
Irene EmahMinistry of Health, Expanded Program on Immunization, Yaoundé, Cameroon.
Serge ElaMother and Child Center, Chantal Biya Foundation, Yaoundé, Cameroon.
Benjamin A DahlGlobal Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States.
Marie KobelaMinistry of Health, Expanded Program on Immunization, Yaoundé, Cameroon.
Kathleen F CavallaroGlobal Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States.
Georges Alain Etoundi MballaMinistry of Health, Direction of Disease Control, Yaoundé, Cameroon.
Jon R GenstchDivision of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States.
Michael D BowenDivision of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States.
Paul Koki NdomboMother and Child Center, Chantal Biya Foundation, Yaoundé, Cameroon.
Centre International De Reference Chantal Biya · CMCenters for Disease Control and Prevention · USMinistry of Public Health · CMNational Center for Immunization and Respiratory Diseases · USUniversity of Limpopo · ZAWWF Cameroon · CM

Funding

Intramural CDC HHS CC999999World Health Organization 001
6 · The paper itself

Abstract

Rotavirus is the most common cause of severe diarrheal disease in children under 5 years of age worldwide. The World Health Organization (WHO) estimated that 453,000 rotavirus-attributable deaths occur annually. Through the WHO, the Rotavirus Sentinel Surveillance Program was established in Cameroon in September 2007 with the Mother and Child Center (MCC) in Yaoundé playing the role of sentinel site and national laboratory for this program. The objectives of this surveillance were to assess the rotavirus disease burden and collect baseline information on rotavirus strains circulating in Cameroon. Diarrheal stool samples were collected in a pediatric hospital from children under 5, using the WHO case definition for rotavirus diarrhea. Antigen detection of rotavirus was performed by using an enzyme immunoassay (EIA). The genotypic characterization was performed using multiplexed semi-nested reverse transcription-polymerase chain reaction (RT-PCR) assays. Between September 2007 and December 2012, 2444 stool samples were received at the MCC laboratory for rotavirus antigen detection, of which 999 (41%) were EIA positive. Among EIA positive samples 898 were genotyped. Genotype prevalence varied each year. Genotype G9P[8] was the dominant type during 2007 (32%) and 2008 (24%), genotype G3P[6] predominated in 2010 (36%) and 2011 (25%), and G1P[8] was predominant in 2012 (44%). The findings showed that the rotavirus disease burden is high and there is a broad range of rotavirus strains circulating in Yaoundé. These data will help measure the impact of vaccination in the future.

Indexed as

Population SurveillanceAge DistributionCameroonChild, PreschoolFecesGastroenteritisGenotypeHistory, 21st CenturyHumansInfantInfant, NewbornRotavirusRotavirus InfectionsSeasonsSpatio-Temporal AnalysisCameroonMolecular epidemiologyRotavirusSurveillance

Identifiers

PMID25220619
PMCPMC9199442
OpenAlexW2045943778

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.