Evidence map›Paper›PMID 25220308›Full record

ArticleNature reviews. Microbiology2014

Reductive genome evolution at both ends of the bacterial population size spectrum.

Bérénice Batut, Carole Knibbe, Gabriel Marais, Vincent Daubin

Abstract read
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In one paragraph

Article in Nature reviews. Microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. A genomic view of Earth's biomes.Nature reviews. Genetics · 2026
    Review
  5. Reductive evolution and genomic reduction inApplied and environmental microbiology · 2025
    Article
  6. Article
  7. Ecosystem relocation on Snowball Earth: Polar-alpine ancestry of the extant surface biosphere?Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Uncovering newMicrobiology spectrum · 2024
    Article
  13. Carbon starvation raises capacities in bacterial antibiotic resistance and viral auxiliary carbon metabolism in soils.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bérénice Batut1] Université Lyon 1, Centre National de la Recherche Scientifique (CNRS), Laboratoire de Biomtrie et Biologie volutive (LBBE), UMR5558, F-69622, France. [2] Université de Lyon, CNRS, French Institute for Research in Computer Science and Automation (INRIA), Institut National des Sciences Appliquées (INSA) de Lyon, Laboratoire d'Informatique en Images et Systèmes d'Information (LIRIS), UMR5205, F-69621, France.
Carole KnibbeUniversité Lyon 1, INRIA, CNRS, LIRIS, UMR5205, F-69622, France.
Gabriel MaraisUniversité Lyon 1, Centre National de la Recherche Scientifique (CNRS), Laboratoire de Biomtrie et Biologie volutive (LBBE), UMR5558, F-69622, France.
Vincent DaubinUniversité Lyon 1, Centre National de la Recherche Scientifique (CNRS), Laboratoire de Biomtrie et Biologie volutive (LBBE), UMR5558, F-69622, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial genomes show substantial variations in size. The smallest bacterial genomes are those of endocellular symbionts of eukaryotic hosts, which have undergone massive genome reduction and show patterns that are consistent with the degenerative processes that are predicted to occur in species with small effective population sizes. However, similar genome reduction is found in some free-living marine cyanobacteria that are characterized by extremely large populations. In this Opinion article, we discuss the different hypotheses that have been proposed to account for this reductive genome evolution at both ends of the bacterial population size spectrum.

Indexed as

Evolution, MolecularGenome SizeBacteriaBuchneraCyanobacteriaGenome, BacterialModels, GeneticPhylogenyProchlorococcus

Identifiers

PMID25220308

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.