Trial reportDevelopmental cognitive neuroscience2015
Reward enhances tic suppression in children within months of tic disorder onset.
Trial report in Developmental cognitive neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Efficacy of differential reinforcement of other behaviors therapy for tic disorder: a meta-analysis.BMC neurology · 2024Pooled it
- Metabolic abnormalities of the cortico‑striato‑thalamo‑cortical circuit of rats with tic disorder.Molecular medicine reports · 2025Article
- EEG power modulation in the sensorimotor regions is critical to motor tic suppression.Frontiers in psychiatry · 2025Article
- Correlating clinical course with baseline subcortical shape in provisional tic disorder.CNS spectrums · 2024Article
- Functional connectivity of the pediatric brain.Neuroradiology · 2024Review
- We've all been wrong about provisional tic disorder.Comprehensive psychiatry · 2024Article
- Quantifying tics: Best practices and design considerations for video-based tic coding in research.Behavior research methods · 2024Article
- Why Tic Severity Changes from Then to Now and from Here to There.Journal of clinical medicine · 2022Review
- Differential age-dependent development of inter-area brain connectivity in term and preterm neonates.Pediatric research · 2022Article
- Identifying Factors Associated with the Recurrence of Tic Disorders.Brain sciences · 2022Article
- Fractality of tics as a quantitative assessment tool for Tourette syndrome.Journal of the Royal Society, Interface · 2022Article
- Correlates and clinical implications of tic suppressibility.Current developmental disorders reports · 2021Article
- TicTimer Web: software for measuring tic suppression remotely.F1000Research · 2020Article
- The Use of Immersive Environments for the Early Detection and Treatment of Neuropsychiatric Disorders.Frontiers in digital health · 2020Article
- Modulation of Frontal Oscillatory Power during Blink Suppression in Children: Effects of Premonitory Urge and Reward.Cerebral cortex communications · 2020Article
- The New Tics study: A Novel Approach to Pathophysiology and Cause of Tic Disorders.Journal of psychiatry and brain science · 2020Article
- Tic Suppression in Children With Recent-Onset Tics Predicts 1-Year Tic Outcome.Journal of child neurology · 2019Article
- Provisional Tic Disorder is not so transient.Scientific reports · 2019Article
- Premonitory Urges and Their Link With Tic Severity in Children and Adolescents With Tic Disorders.Frontiers in psychiatry · 2019Article
- Neonatal brain resting-state functional connectivity imaging modalities.Photoacoustics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Tic disorders are childhood onset neuropsychiatric disorders characterized by motor and/or vocal tics. Research has demonstrated that children with chronic tics (including Tourette syndrome and Chronic Tic Disorder: TS/CTD) can suppress tics, particularly when an immediate, contingent reward is given for successful tic suppression. As a diagnosis of TS/CTD requires tics to be present for at least one year, children in these tic suppression studies had been living with tics for quite some time. Thus, it is unclear whether the ability to inhibit tics is learned over time or present at tic onset. Resolving that issue would inform theories of how tics develop and how behavior therapy for tics works. We investigated tic suppression in school-age children as close to the time of tic onset as possible, and no later than six months after onset. Children were asked to suppress their tics both in the presence and absence of a contingent reward. Results demonstrated that these children, like children with TS/CTD, have some capacity to suppress tics, and that immediate reward enhances that capacity. These findings demonstrate that the modulating effect of reward on inhibitory control of tics is present within months of tic onset, before tics have become chronic.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.