Evidence map›Paper›PMID 25219650›Full record

ArticleThe Journal of investigative dermatology2014

Cells of origin in skin cancer.

Jürgen C Becker, Axel Zur Hausen

Abstract readComment
PubMed Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Evidence of an epithelial origin of Merkel cell carcinoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022
    Article
  5. Review
  6. Article
  7. Daily Lifestyle and Cutaneous Malignancies.International journal of molecular sciences · 2021
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
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  14. Review
  15. Article
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  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jürgen C BeckerDivision of General Dermatology, Medical University of Graz, Graz, Austria. Electronic address: juergen.becker@medunigraz.at.
Axel Zur HausenDepartment of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult skin stem cells do not protect their genome by asymmetric chromosome segregation; thus, they are prone to accumulating oncogenic mutations.

Indexed as

9,10-Dimethyl-1,2-benzanthraceneAnimalsBasal Cell CarcinomaCarcinogenesisCD4-Positive T-LymphocytesEpidermisPatched ReceptorsReceptors, Cell SurfaceSkin NeoplasmsTetradecanoylphorbol Acetate9,10-Dimethyl-1,2-benzanthracenePatched ReceptorsReceptors, Cell SurfaceTetradecanoylphorbol Acetate

Identifiers

PMID25219650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.