ArticleNeuroscience letters2014
Tracheosyringeal nerve transection in juvenile male zebra finches decreases BDNF in HVC and RA and the projection between them.
Article in Neuroscience letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Inhibition of TrkB limits development of the zebra finch song system.Brain research · 2016Article
- Genetic regulation of sex differences in songbirds and lizards.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
This study investigated relationships among disruption of normal vocal learning, brain-derived neurotrophic factor (BDNF), and the morphology of song nuclei in juvenile male zebra finches. The tracheosyringeal nerves were bilaterally transected at post-hatching day 20-25, so that the animals could not properly develop species-typical vocalizations. BDNF protein and the projection from HVC to the robust nucleus of the arcopallium (RA) were quantified during the sensorimotor integration phase of song development. The manipulation decreased the number of BDNF cells in HVC and RA, the volume of these areas defined by BDNF labeling, and the projection from HVC to RA. BDNF was not affected in Area X or the lateral magnocellular nucleus of the anterior nidopallium (LMAN). Thus, inhibition of a bird's ability to practice and/or to hear its own typically developing song specifically diminishes BDNF expression in cortical motor regions required for song production.
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Registered trials
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