Evidence map›Paper›PMID 25217566›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2014

Yeast mutation accumulation experiment supports elevated mutation rates at highly transcribed sites.

Xiaoshu Chen, Jianzhi Zhang

Abstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. What Has Genomics Taught An Evolutionary Biologist?Genomics, proteomics & bioinformatics · 2023
    Review
  8. Review
  9. Recent insights into the evolution of mutation rates in yeast.Current opinion in genetics & development · 2022
    Review
  10. Article
  11. Estimating maximal microbial growth rates from cultures, metagenomes, and single cells via codon usage patterns.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Reply to Chen and Zhang: On interpreting genome-wide trends from yeast mutation accumulation data.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Xiaoshu ChenDepartment of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109.
Jianzhi ZhangDepartment of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109 jianzhi@umich.edu.

Funding

Pleiotropy: patterns, mechanisms, and evolutionary consequencesR01GM103232 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZHANG, JIANZHI · 2013 to 2020
$1.8M
NIGMS NIH HHS R01 GM103232
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mutation RateGenetic VariationSaccharomyces cerevisiae

Identifiers

PMID25217566
PMCPMC4191789

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.