ArticleThe Plant cell2014
Hypomethylated pollen bypasses the interploidy hybridization barrier in Arabidopsis.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 60 citations in OpenAlex.
- Epigenetic gene regulation in plants and its potential applications in crop improvement.Nature reviews. Molecular cell biology · 2025Review
- Parental dialectic: Epigenetic conversations in endosperm.Current opinion in plant biology · 2024Review
- Targeted suppression of siRNA biogenesis in Arabidopsis pollen promotes triploid seed viability.Nature communications · 2024Article
- Molecular basis and evolutionary drivers of endosperm-based hybridization barriers.Plant physiology · 2024Review
- Maternal control of triploid seed development by the TRANSPARENT TESTA 8 (TT8) transcription factor in Arabidopsis thaliana.Scientific reports · 2023Article
- Genetic and environmental manipulation ofFrontiers in plant science · 2023Article
- Bypassing reproductive barriers in hybrid seeds using chemically induced epimutagenesis.The Plant cell · 2022Article
- Will epigenetics be a key player in crop breeding?Frontiers in plant science · 2022Review
- Plant 3D genomics: the exploration and application of chromatin organization.The New phytologist · 2021Review
- Transgenerational effect of mutants in the RNA-directed DNA methylation pathway on the triploid block in Arabidopsis.Genome biology · 2021Article
- OsYUC11-mediated auxin biosynthesis is essential for endosperm development of rice.Plant physiology · 2021Article
- Loss of Small-RNA-Directed DNA Methylation in the Plant Cell Cycle Promotes Germline Reprogramming and Somaclonal Variation.Current biology : CB · 2021Article
- Hybrid seed incompatibility in Capsella is connected to chromatin condensation defects in the endosperm.PLoS genetics · 2021Article
- Article
- Genomic imprinting in plants-revisiting existing models.Genes & development · 2020Review
- Article
- Paternally Acting Canonical RNA-Directed DNA Methylation Pathway Genes Sensitize Arabidopsis Endosperm to Paternal Genome Dosage.The Plant cell · 2019Article
- Auxin regulates endosperm cellularization inGenes & development · 2019Article
- Aberrant imprinting may underlie evolution of parthenogenesis.Scientific reports · 2018Article
- Transposon-derived small RNAs triggered by miR845 mediate genome dosage response in Arabidopsis.Nature genetics · 2018Article
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
Plants of different ploidy levels are separated by a strong postzygotic hybridization barrier that is established in the endosperm. Deregulated parent-of-origin specific genes cause the response to interploidy hybridizations, revealing an epigenetic basis of this phenomenon. In this study, we present evidence that paternal hypomethylation can bypass the interploidy hybridization barrier by alleviating the requirement for the Polycomb Repressive Complex 2 (PRC2) in the endosperm. PRC2 epigenetically regulates gene expression by applying methylation marks on histone H3. Bypass of the barrier is mediated by suppressed expression of imprinted genes. We show that the hypomethylated pollen genome causes de novo CHG methylation directed to FIS-PRC2 target genes, suggesting that different epigenetic modifications can functionally substitute for each other. Our work presents a method for the generation of viable triploids, providing an impressive example of the potential of epigenome manipulations for plant breeding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.