ReviewBriefings in functional genomics2014
Fungal cellulose degradation by oxidative enzymes: from dysfunctional GH61 family to powerful lytic polysaccharide monooxygenase family.
Review in Briefings in functional genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 81 citations in OpenAlex.
- Fungal Community Assembly in Standing Deadwood: Stochastic vs. Deterministic Processes Across Decay Stages.Environmental microbiology reports · 2025Article
- Apiospora arundinis, a panoply of carbohydrate-active enzymes and secondary metabolites.IMA fungus · 2024Article
- Recent advances in the efficient degradation of lignocellulosic metabolic networks by lytic polysaccharide monooxygenase.Acta biochimica et biophysica Sinica · 2023Review
- A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen Cryptococcus neoformans.PLoS pathogens · 2023Article
- Structure of a C1/C4-oxidizing AA9 lytic polysaccharide monooxygenase from the thermophilic fungus Malbranchea cinnamomea.Acta crystallographica. Section D, Structural biology · 2021Article
- C-type cytochrome-initiated reduction of bacterial lytic polysaccharide monooxygenases.The Biochemical journal · 2021Article
- Hallmarks of Basidiomycete Soft- and White-Rot in Wood-Decay -Omics Data of TwoMicroorganisms · 2021Article
- Identification and characterization of a novel AA9-type lytic polysaccharide monooxygenase from a bagasse metagenome.Applied microbiology and biotechnology · 2021Article
- Enzymatic processing of lignocellulosic biomass: principles, recent advances and perspectives.Journal of industrial microbiology & biotechnology · 2020Review
- Studies of Cellulose and Starch Utilization and the Regulatory Mechanisms of Related Enzymes in Fungi.Polymers · 2020Review
- Progress in Ameliorating Beneficial Characteristics of Microbial Cellulases by Genetic Engineering Approaches for Cellulose Saccharification.Frontiers in microbiology · 2020Review
- Article
- A Lytic Polysaccharide Monooxygenase from a White-Rot Fungus Drives the Degradation of Lignin by a Versatile Peroxidase.Applied and environmental microbiology · 2019Article
- Construction of a cellulose-metabolizing Komagataella phaffii (Pichia pastoris) by co-expressing glucanases and β-glucosidase.Applied microbiology and biotechnology · 2018Article
- Biotechnology Potential of Marine Fungi Degrading Plant and Algae Polymeric Substrates.Frontiers in microbiology · 2018Review
- Genetic engineering of Trichoderma reesei cellulases and their production.Microbial biotechnology · 2017Review
- Six Key Traits of Fungi: Their Evolutionary Origins and Genetic Bases.Microbiology spectrum · 2017Article
- Systems analysis in Cellvibrio japonicus resolves predicted redundancy of β-glucosidases and determines essential physiological functions.Molecular microbiology · 2017Article
- Xylose induces cellulase production inBiotechnology for biofuels · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our understanding of fungal cellulose degradation has shifted dramatically in the past few years with the characterization of a new class of secreted enzymes, the lytic polysaccharide monooxygenases (LPMO). After a period of intense research covering structural, biochemical, theoretical and evolutionary aspects, we have a picture of them as wedge-like copper-dependent metalloenzymes that on reduction generate a radical copper-oxyl species, which cleaves mainly crystalline cellulose. The main biological function lies in the synergism of fungal LPMOs with canonical hydrolytic cellulases in achieving efficient cellulose degradation. Their important role in cellulose degradation is highlighted by the wide distribution and often numerous occurrences in the genomes of almost all plant cell-wall degrading fungi. In this review, we provide an overview of the latest achievements in LPMO research and consider the open questions and challenges that undoubtedly will continue to stimulate interest in this new and exciting group of enzymes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.