Impact of de-escalation on ICU patients' prognosis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric).Intensive care medicine · 2015
   Guideline
2. Antibiotic De-Escalation in Emergency General Surgery.Antibiotics (Basel, Switzerland) · 2022
   Article
3. De-escalation empirical antibiotic therapy improved survival for patients with severe aplastic anemia treated with antithymocyte globulin.Medicine · 2017
   Observational
4. Pros and cons of using biomarkers versus clinical decisions in start and stop decisions for antibiotics in the critical care setting.Intensive care medicine · 2015
   Review
5. A Simulation Study Reveals Lack of Pharmacokinetic/Pharmacodynamic Target Attainment in De-escalated Antibiotic Therapy in Critically Ill Patients.Antimicrobial agents and chemotherapy · 2015
   Article
6. Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria.Intensive care medicine · 2015
   Review

Corrections and comments

• Comment on
  De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial.2014

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as