ArticleNeurology2014
Why brain death is considered death and why there should be no confusion.
Article in Neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Bereavement interventions to support informal caregivers in the intensive care unit: a systematic review.BMC palliative care · 2021Pooled it
- Prioritization of Ethical Themes When Surrogates Object to Technology Removal After Brain Death Determination.Neurocritical care · 2025Review
- Themes in the Management of Pediatric Brain Death Contestation: Exploratory Qualitative Work From Multidisciplinary Health Professionals in the United States.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
- Death determination by neurologic criteria-what do families understand?Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Article
- Healthcare Professionals' Understandings of the Definition and Determination of Death: A Scoping Review.Transplantation direct · 2022Article
- The intractable problems with brain death and possible solutions.Philosophy, ethics, and humanities in medicine : PEHM · 2021Review
- A Framework for Revisiting Brain Death: Evaluating Awareness and Attitudes Toward the Neuroscientific and Ethical Debate Around the American Academy of Neurology Brain Death Criteria.Journal of intensive care medicine · 2021Article
- Does the Uniform Determination of Death Act Need to Be Revised?The Linacre quarterly · 2020Article
- Redefining Death: Urgent Need to Evolve toward a Homogeneous Definition of Death in India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019Article
- Update of the diagnostic criteria of brain death: application and training of physicians.Revista Brasileira de terapia intensiva · 2019Article
- The Relevance of Irreversible Loss of Brain Function as a Reliable Sign of Death.Deutsches Arzteblatt international · 2018Review
- Disputes in the Declaration of Brain Death: A Case Illustration.Journal of pediatric intensive care · 2017Review
- Current controversies in brain death determination.Nature reviews. Neurology · 2017Review
- When Brain Death Belies Belief.Journal of religion and health · 2016Review
- Informed consent for the diagnosis of brain death: a conceptual argument.Philosophy, ethics, and humanities in medicine : PEHM · 2016Article
- Bioethics, Religion, and Public Policy: Intersections, Interactions, and Solutions.Journal of religion and health · 2016Review
- [Non-heart-beating donors are ineligible].Der Nervenarzt · 2016Article
- End of Life and Palliative Care in Neurology: Does Autonomy Matter?Annals of Indian Academy of NeurologyArticle
- Optimization of conditions for apnea testing in a hypoxemic brain dead patient.Revista Brasileira de terapia intensivaArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurologic determination of brain death is a complex assessment that may be misunderstood by nonspecialists and families. Recent guidelines clarify how to proceed with such an examination and are available to physicians, with the time of death in adults and children being determined by the last defining test-the apnea test. This core principle in neurology has been challenged recently in court and resulted in an unprecedented continuation of care in a 13-year-old child declared dead. This review comments on the medical, legal, and ethical quandaries introduced by this case and highlights the major elements of consensus on matters related to brain death that have been forged over 3 decades of sustained medical and societal debate. A clear appreciation by physicians and the public of the diagnostic determination of death following loss of brain function will help to prevent similar conflicts from occurring in the future.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.