ArticleApplied and environmental microbiology2014
Absolute Humidity Influences the Seasonal Persistence and Infectivity of Human Norovirus.
Article in Applied and environmental microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Development of a functional and disinfectable sewage vent high-efficiency particulate air filter system and its validation using vaporized hydrogen peroxide.Applied and environmental microbiology · 2026Article
- Seasonal Trends of Major Respiratory, Gastrointestinal, and Other Viral Infections in Korea: An Analysis Before, During, and After the Coronavirus Disease 2019 Pandemic.Annals of laboratory medicine · 2026Review
- Capsid and genome damage are the leading inactivation mechanisms of aerosolized porcine respiratory coronavirus at different relative humidities.Applied and environmental microbiology · 2025Article
- Article
- Association between detection rate of norovirus GII and climatic factors in the Northwest Amazon region.Heliyon · 2024Article
- Spatio-temporal distribution and influencing factors of norovirus outbreaks in Beijing, China from 2016 to 2020.BMC infectious diseases · 2023Article
- The Impact of Heating, Ventilation, and Air-Conditioning Design Features on the Transmission of Viruses, Including SARS-CoV-2: Overview of Reviews.Interactive journal of medical research · 2022Review
- Role of bioaerosol in virus transmission and material-based countermeasures.Exploration (Beijing, China) · 2022Review
- Investigating the effects of absolute humidity and movement on COVID-19 seasonality in the United States.Scientific reports · 2022Article
- Norovirus GII.2[P16] strain in Shenzhen, China: a retrospective study.BMC infectious diseases · 2021Article
- Analysis on the risk of respiratory virus transmission by air conditioning system operation based on experimental evidence.Environmental science and pollution research international · 2021Article
- Nanoscale Wetting of Single Viruses.Molecules (Basel, Switzerland) · 2021Article
- Risk factors for norovirus infection in healthcare workers during nosocomial outbreaks: a cross-sectional study.Antimicrobial resistance and infection control · 2021Article
- Survival and Inactivation by Advanced Oxidative Process of Foodborne Viruses in Model Low-Moisture Foods.Food and environmental virology · 2021Article
- Possible transmission of viruses from contaminated human feces and sewage: Implications for SARS-CoV-2.The Science of the total environment · 2021Article
- Aerosolization and recovery of viable murine norovirus in an experimental setup.Scientific reports · 2020Article
- Investigating the Potential for Ultraviolet Light to Modulate Morbidity and Mortality From COVID-19: A Narrative Review and Update.Frontiers in cardiovascular medicine · 2020Review
- Specific Interactions between Human Norovirus and Environmental Matrices: Effects on the Virus Ecology.Viruses · 2019Review
- Predicting Directions of Changes in Genotype Proportions Between Norovirus Seasons in Japan.Frontiers in microbiology · 2019Article
- Daily humidity oscillation regulates the circadian clock to influence plant physiology.Nature communications · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Norovirus (NoV) is one of the main causative agents of acute gastroenteritis worldwide. In temperate climates, outbreaks peak during the winter season. The mechanism by which climatic factors influence the occurrence of NoV outbreaks is unknown. We hypothesized that humidity is linked to NoV seasonality. Human NoV is not cultivatable, so we used cultivatable murine norovirus (MNV) as a surrogate to study its persistence when exposed to various levels of relative humidity (RH) from low (10% RH) to saturated (100% RH) conditions at 9 and 25°C. In addition, we conducted similar experiments with virus-like particles (VLPs) from the predominant GII-4 norovirus and studied changes in binding patterns to A, B, and O group carbohydrates that might reflect capsid alterations. The responses of MNV and VLP to humidity were somewhat similar, with 10 and 100% RH exhibiting a strong conserving effect for both models, whereas 50% RH was detrimental for MNV infectivity and VLP binding capacity. The data analysis suggested that absolute humidity (AH) rather than RH is the critical factor for keeping NoV infectious, with an AH below 0.007 kg water/kg air being favorable to NoV survival. Retrospective surveys of the meteorological data in Paris for the last 14 years showed that AH average values have almost always been below 0.007 kg water/kg air during the winter (i.e., 0.0046 ± 0.0014 kg water/kg air), and this finding supports the fact that low AH provides an ideal condition for NoV persistence and transmission during cold months.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.