Evidence map›Paper›PMID 25216985›Full record

ReviewCurrent HIV/AIDS reports2014

Combination HIV prevention interventions: the potential of integrated behavioral and biomedical approaches.

Jennifer L Brown, Jessica M Sales, Ralph J DiClemente

Open access · bronzeAbstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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  8. Viral Pandemics of the Last Four Decades: Pathophysiology, Health Impacts and Perspectives.International journal of environmental research and public health · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jennifer L BrownDepartment of Psychological Sciences, Texas Tech University, MS 2051, Lubbock, TX, 79409-2051, USA, jennifer.brown@ttu.edu.
Jessica M Sales
Ralph J DiClemente
Emory University · USTexas Tech University · US

Funding

Reducing Alcohol-Related HIV Risk in African American FemalesR01AA018096 · NIAAA · EMORY UNIVERSITY · PI DICLEMENTE, RALPH J, MONAHAN, JENNIFER L · 2010 to 2014
$3.8M
KIIDS: Knowing about intervention implementation in Detention SitesU01DA036233 · NIDA · EMORY UNIVERSITY · PI DICLEMENTE, RALPH J, SALES, JESSICA A · 2013 to 2017
$3.5M
Factors Associated with Teens' Non-Responsiveness to HIV InterventionK01MH085506 · NIMH · EMORY UNIVERSITY · PI SALES, JESSICA A · 2009 to 2013
$686k
Impact of Drug Use Treatment on HIV Risk Behaviors: An Integrative Data AnalysisR03DA037786 · NIDA · UNIVERSITY OF CINCINNATI · PI BROWN, JENNIFER L · 2014 to 2015
$303k
NIAAA NIH HHS 1R01AA018096NIAAA NIH HHS R01 AA018096NIDA NIH HHS 1U01DA0362233NIDA NIH HHS R03 DA037786NIDA NIH HHS R03DA0377860NIDA NIH HHS U01 DA036233NIMH NIH HHS K01 MH085506NIMH NIH HHS K01MH085506
6 · The paper itself

Abstract

Combination HIV prevention interventions that integrate efficacious behavioral and biomedical strategies offer the potential to reduce new HIV infections. We overview the efficacy data for three biomedical HIV prevention approaches, namely microbicides, pre-exposure prophylaxis (PrEP), and HIV vaccination; review factors associated with differential acceptability and uptake of these methods; and suggest strategies to optimize the effectiveness and dissemination of combination HIV prevention approaches. A narrative review was conducted highlighting key efficacy data for microbicides, PrEP, and an HIV vaccination and summarizing acceptability data for each of the three biomedical HIV prevention approaches. Recommendations for the integration and dissemination of combined behavioral and biomedical HIV prevention approaches are provided. To date, microbicides and an HIV vaccination have demonstrated limited efficacy for the prevention of HIV. However, PrEP has demonstrated efficacy in reducing HIV incident infections. A diverse array of factors influences both hypothetical willingness and actual usage of each biomedical prevention method. Strategies to effectively integrate and evaluate combination HIV prevention interventions are urgently needed.

Indexed as

AIDS VaccinesAnti-HIV AgentsFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansMalePre-Exposure ProphylaxisAIDS VaccinesAnti-HIV Agents

Identifiers

PMID25216985
PMCPMC4358895
OpenAlexW1995945110

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.