Evidence map›Paper›PMID 25216812›Full record

ArticleJournal of substance abuse treatment2015

Misuse of atypical antipsychotics in conjunction with alcohol and other drugs of abuse.

Tara Malekshahi, Nina Tioleco, Nahima Ahmed, Aimee N C Campbell, Deborah Haller

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of substance abuse treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
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  9. Review
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Novel psychoactive substances of interest for psychiatry.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2015
    Article
  15. Article
  16. Prescription drug abuse: from epidemiology to public policy.Journal of substance abuse treatment · 2015
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tara MalekshahiMount Sinai St. Luke's and Roosevelt Hospitals, New York, NY, USA.
Nina TiolecoMount Sinai St. Luke's and Roosevelt Hospitals, New York, NY, USA.
Nahima AhmedMount Sinai St. Luke's and Roosevelt Hospitals, New York, NY, USA.
Aimee N C CampbellMount Sinai St. Luke's and Roosevelt Hospitals, New York, NY, USA; Columbia University Medical Center, College of Physicians and Surgeons, Department of Psychiatry, New York, NY, USA. Electronic address: acampbell@chpnet.org.
Deborah HallerIcahn School of Medicine at Mount Sinai, New York, NY, USA.
St. Luke's-Roosevelt Hospital Center · USIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-medical use of atypical antipsychotics by substance abusers has been reported in the literature, although no detailed studies exist. Among 429 addiction treatment inpatients screened, 73 (17.0%) reported misuse of antipsychotics with alcohol, opioids, cocaine, methamphetamine and/or cannabis; 39 (9.1%) within the past year. Of past year misusers, 25 (64.1%) were interviewed. Most were male (76.0%), non-Caucasian (56.0%), and polysubstance abusers (84.0%). Quetiapine, the most abused drug (96.0%), was obtained primarily from doctors (52.0%) and family/friends (48.0%). Reasons for use included to "recover" from other substances (66.7%), "enhance" the effects of other substances (25.0%), and "experiment" (20.8%). The most frequently reported positive effect was "feeling mellow" (75.0%); negative effects were consistent with antipsychotic use (e.g., feeling thirsty, trouble concentrating). Compared to a normative sample of inpatient substance abusers, ASI composite scores were higher. Findings suggest that physicians should assess for use/misuse of atypical antipsychotics among patients with addiction.

Indexed as

Antipsychotic AgentsDibenzothiazepinesAdultAlcoholismBehavior, AddictiveFemaleHumansMaleMiddle AgedPrescription Drug MisuseQuetiapine FumarateSex FactorsAntipsychotic AgentsDibenzothiazepinesQuetiapine FumarateAtypical antipsychoticInpatient detox/rehabMisuseOff-labelSubstance abuse

Identifiers

PMID25216812
OpenAlexW2049935054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.