ArticleInternational surgery
Glasgow Prognostic Score (GPS) can be a useful indicator to determine prognosis of patients with colorectal carcinoma.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: Systematic review and meta-analysis.Scientific reports · 2017Pooled it
- Prognostic Value of Pre-Treatment Systemic Inflammatory Markers in Pediatric Unilateral Wilms Tumor.Cancers · 2026Article
- Predictive Value of the Glasgow Prognostic Score for Prognosis in Patients with Hypopharyngeal Squamous Cell Carcinoma Treated with Curative Radiotherapy.Journal of clinical medicine · 2025Article
- Novel tumor marker index combining carcinoembryonic antigen and carbohydrate antigen 19-9: New prognostic factor for metastatic colorectal cancer.World journal of gastrointestinal oncology · 2025Article
- Comparison of inflammatory markers before and after nanoliposomal irinotecan and fluorouracil with folic acid in patients with pancreatic cancer: results from the NAPOLEON-2 study (NN-2302).Therapeutic advances in medical oncology · 2025Article
- The prognostic impact of C-reactive protein and albumin in patients diagnosed with acute myeloid leukaemia.EJHaem · 2024Article
- Role of the Modified Glasgow Prognostic Score (mGPS) as a Prognostic Factor in Metastatic Colorectal Cancer.Cureus · 2024Article
- The Association of Inflammatory Related Markers with the Prognosis in Elderly Patients with Colorectal Cancer.Cancer management and research · 2024Article
- The Correlation of Malnutrition with Mortality and Morbidity According to Global Initiative on Malnutrition Criteria in the Palliative Care Unit.Florence Nightingale journal of nursing · 2023Article
- Significance of C-reactive protein in patients with chronic myelomonocytic leukemia.Wiener medizinische Wochenschrift (1946) · 2023Article
- Protein expression of S100A2 reveals it association with patient prognosis and immune infiltration profile in colorectal cancer.Journal of Cancer · 2023Article
- Systemic Inflammation is Associated with Cardiometabolic Risk Factors and Clinical Outcomes.Journal of inflammation research · 2022Article
- Visceral fat area and albumin based nutrition-related prognostic index model could better stratify the prognosis of diffuse large B-cell lymphoma in rituximab era.Frontiers in nutrition · 2022Article
- The systemic-level repercussions of cancer-associated inflammation mediators produced in the tumor microenvironment.Frontiers in endocrinology · 2022Review
- Inflammatory biomarkers as independent prognosticators of 28-day mortality for COVID-19 patients admitted to general medicine or ICU wards: a retrospective cohort study.Internal and emergency medicine · 2021Article
- Review
- Baseline nutritional status could be a predictor for radiation esophagitis in esophageal cancer patients undergoing radiotherapy.Annals of translational medicine · 2020Article
- Modified Glasgow prognostic score can predict survival of muscle invasive bladder cancer patients after radiotherapy.Journal of radiation research · 2020Article
- Prognostic role of a new index (multi inflammatory index) in patients with metastatic colorectal cancer: results from the randomized ITACa trial.Therapeutic advances in medical oncology · 2020Article
- Clinical prognostic scores for patients with thymic epithelial tumors.Scientific reports · 2019Article
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Abstract
The Glasgow Prognostic Score (GPS), an inflammation-based score, has been used to predict the biologic behavior of malignant tumors. The aim of the current study was to elucidate a further significance of GPS in colorectal carcinoma. Correlation of GPS and modified GPS (mGPS), which are composed of combined score provided for serum elevation of C-reactive protein and hypoalbuminemia examined before surgical treatment, with clinicopathologic features was investigated in 272 patients with colorectal carcinoma. Survival of GPS 1 patients was significantly worse than that of GPS 0 patients (P= 0.009), and survival of GPS 2 patients was significantly worse than that of GPS 1 patients (P < 0.0001). Similarly, survival of mGPS 1 patients was significantly worse than that of mGPS 0 patients (P = 0.009), and survival of mGPS 2 patients was significantly worse than that of mGPS 1 patients (P = 0.0006). Multivariate analysis demonstrated that GPS (P < 0.0001) as well as tumor stage (P= 0.004) and venous invasion (P = 0.011) were factors independently associated with worse prognosis. Both GPS and mGPS could classify outcome of patients with a clear stratification, and could be applied as prognostic indicators in colorectal carcinoma.
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