ArticleNature communications2014
Comparative genome sequencing reveals genomic signature of extreme desiccation tolerance in the anhydrobiotic midge.
Article in Nature communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed.
- Haplotype-resolved genome of a dry-preservable cell line reveals chromosome evolution and DNA damage.Life science alliance · 2026Article
- Desiccation tolerance mechanisms in the green lineage and beyond.The New phytologist · 2026Review
- Lessons from the slide preparation: A new species ofZooKeys · 2026Article
- Biomolecular condensates-Prerequisites for anhydrobiosis?Protein science : a publication of the Protein Society · 2025Review
- Life on the dry side: a roadmap to understanding desiccation tolerance and accelerating translational applications.Nature communications · 2025Review
- Exogenous LEA proteins expression enhances cold tolerance in mammalian cells by reducing oxidative stress.Scientific reports · 2025Article
- Shared Features Underlying Compact Genomes and Extreme Habitat Use in Chironomid Midges.Genome biology and evolution · 2024Article
- The chromosome-level genome assembly of the giant dobsonfly Acanthacorydalis orientalis (McLachlan, 1899).Scientific data · 2024Article
- A sodium-dependent trehalose transporter contributes to anhydrobiosis in insect cell line, Pv11.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Two chromosome-level genomes of Smittia aterrima and Smittia pratorum (Diptera, Chironomidae).Scientific data · 2024Article
- Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga.BMC biology · 2024Article
- Effective methods for immobilization of non-adherent Pv11 cells while maintaining their desiccation tolerance.Cytotechnology · 2023Article
- Population Genomics of Two Closely Related Anhydrobiotic Midges Reveals Differences in Adaptation to Extreme Desiccation.Genome biology and evolution · 2023Article
- Dehydration Dynamics in Terrestrial Arthropods: From Water Sensing to Trophic Interactions.Annual review of entomology · 2023Review
- Recapitulation of the embryonic transcriptional program in holometabolous insect pupae.Scientific reports · 2022Article
- Deciphering the Biological Enigma-Genomic Evolution Underlying Anhydrobiosis in the Phylum Tardigrada and the ChironomidInsects · 2022Review
- High quality genome assembly of the anhydrobiotic midge provides insights on a single chromosome-based emergence of extreme desiccation tolerance.NAR genomics and bioinformatics · 2022Article
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- The Orthodox Dry Seeds Are Alive: A Clear Example of Desiccation Tolerance.Plants (Basel, Switzerland) · 2021Review
3 more citing papers are in PubMed but not listed here.
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Authors and funding
28 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anhydrobiosis represents an extreme example of tolerance adaptation to water loss, where an organism can survive in an ametabolic state until water returns. Here we report the first comparative analysis examining the genomic background of extreme desiccation tolerance, which is exclusively found in larvae of the only anhydrobiotic insect, Polypedilum vanderplanki. We compare the genomes of P. vanderplanki and a congeneric desiccation-sensitive midge P. nubifer. We determine that the genome of the anhydrobiotic species specifically contains clusters of multi-copy genes with products that act as molecular shields. In addition, the genome possesses several groups of genes with high similarity to known protective proteins. However, these genes are located in distinct paralogous clusters in the genome apart from the classical orthologues of the corresponding genes shared by both chironomids and other insects. The transcripts of these clustered paralogues contribute to a large majority of the mRNA pool in the desiccating larvae and most likely define successful anhydrobiosis. Comparison of expression patterns of orthologues between two chironomid species provides evidence for the existence of desiccation-specific gene expression systems in P. vanderplanki.
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