Evidence map›Paper›PMID 25216287›Full record

ArticleMagnetic resonance in medicine2014

ECG and navigator-free four-dimensional whole-heart coronary MRA for simultaneous visualization of cardiac anatomy and function.

Jianing Pang, Behzad Sharif, Zhaoyang Fan, Xiaoming Bi, Reza Arsanjani, Daniel S Berman, Debiao Li

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

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  14. Measuring biventricular function and left atrial volume in a single five-dimensional whole-heart cardiovascular magnetic resonance scan at 0.55T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
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  16. Review
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  19. Optimal Protocol for Contrast-enhanced Free-running 5D Whole-heart Coronary MR Angiography at 3T.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jianing PangDepartment of Radiology and Biomedical Engineering, Northwestern University, Chicago, Illinois, USA; Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Behzad Sharif
Zhaoyang Fan
Xiaoming Bi
Reza Arsanjani
Daniel S Berman
Debiao Li

Funding

Magnetic Resonance Imaging of Coronary Arteries at 3.OTR01EB002623 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LI, DEBIAO · 2003 to 2012
$2.6M
Self-Gated, Motion-Resolved Whole-Heart Coronary MRA with Isotropic ResolutionR01HL038698 · NHLBI · WASHINGTON UNIVERSITY · PI LI, DEBIAO · 1990 to 2010
$2.5M
Accurate Perfusion MRI for Improved Diagnosis of Microvascular Coronary DiseaseK99HL124323 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI SHARIF, BEHZAD · 2014 to 2015
$276k
NHLBI NIH HHS HL38698NHLBI NIH HHS K99 HL124323NHLBI NIH HHS R01 HL038698NIBIB NIH HHS EB002623NIBIB NIH HHS R01 EB002623
6 · The paper itself

Abstract

purposeTo develop a cardiac and respiratory self-gated four-dimensional (4D) coronary MRA technique for simultaneous cardiac anatomy and function visualization.

methodsA contrast-enhanced, ungated spoiled gradient echo sequence with self-gating (SG) and 3DPR trajectory was used for image acquisition. Data were retrospectively binned into different cardiac and respiratory phases based on information extracted from SG projections using principal component analysis. Each cardiac phase was reconstructed using a respiratory motion-corrected self-calibrating SENSE framework, and those belong to the quiescent period were retrospectively combined for coronary visualization. Healthy volunteer studies were conducted to evaluate the efficacy of the SG method, the accuracy of the left ventricle (LV) function parameters and the quality of coronary artery visualization.

resultsSG performed reliably for all subjects including one with poor electrocardiogram (ECG). The LV function parameters showed excellent agreement with those from a conventional cine protocol. For coronary imaging, the proposed method yielded comparable apparent signal to noise ratio and coronary sharpness and lower apparent contrast to noise ratio on three subjects compared with an ECG and navigator-gated Cartesian protocol and an ECG-gated, respiratory motion-corrected 3DPR protocol.

conclusionA fully self-gated 4D whole-heart imaging technique was developed, potentially allowing cardiac anatomy and function assessment from a single measurement.

Indexed as

ElectrocardiographyAdultCardiac-Gated Imaging TechniquesContrast MediaCoronary VesselsFemaleHealthy VolunteersHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance AngiographyMalePrincipal Component AnalysisRespiratory-Gated Imaging TechniquesRetrospective StudiesContrast Media3D radial acquisitioncine imagingcoronary MRAself-gating

Identifiers

PMID25216287
PMCPMC4198505

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.