Evidence map›Paper›PMID 25215885›Full record

ReviewCurrent opinion in structural biology2014

The structural biology of phenazine biosynthesis.

Wulf Blankenfeldt, James F Parsons

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

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  17. Article
  18. Spatial heterogeneity in biofilm metabolism elicited by local control of phenazine methylation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Review
  20. The two faces of pyocyanin - why and how to steer its production?World journal of microbiology & biotechnology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wulf BlankenfeldtHelmholtz Centre for Infection Research, Structure and Function of Proteins, Inhoffenstr. 7, 38124 Braunschweig, Germany. Electronic address: wulf.blankenfeldt@helmholtz-hzi.de.
James F ParsonsInstitute for Bioscience and Biotechnology Research, University of Maryland, 9600 Gudelsky Drive, Rockville, MD 20850, USA. Electronic address: parsonsj@umd.edu.

Funding

Biochemistry of Phenazine Production in Pseudomonas aeruginosaR01AI067530 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI PARSONS, JAMES F · 2006 to 2009
$1.2M
NIAID NIH HHS R01 AI067530
6 · The paper itself

Abstract

The phenazines are a class of over 150 nitrogen-containing aromatic compounds of bacterial and archeal origin. Their redox properties not only explain their activity as broad-specificity antibiotics and virulence factors but also enable them to function as respiratory pigments, thus extending their importance to the primary metabolism of phenazine-producing species. Despite their discovery in the mid-19th century, the molecular mechanisms behind their biosynthesis have only been unraveled in the last decade. Here, we review the contribution of structural biology that has led to our current understanding of phenazine biosynthesis.

Indexed as

Archaeal ProteinsBacterial ProteinsChorismic AcidOxidation-ReductionPhenazinesProtein ConformationVirulence FactorsArchaeal ProteinsBacterial ProteinsChorismic AcidPhenazinesVirulence Factors

Identifiers

PMID25215885
PMCPMC4268259

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.